Torasemide Impurity 16 CAS CATO-C4X-183616

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-183616
Molecular FormulaC6H6ClNO3S
Molecular Weight207.63 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Torasemide Impurity 16 CAS CATO-C4X-183616 chemical structure

Description

CATO supplies Torasemide Impurity 16 (CAS CATO-C4X-183616), a pharmacopoeial impurity reference standard (molecular formula C6H6ClNO3S, MW 207.63 g/mol) used for the identification and quantification of trace impurities in APIs.

Torasemide Impurity 16 (C6H6ClNO3S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

As a certified reference material (CRM), Torasemide Impurity 16 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H6ClNO3S
Molecular Weight207.63 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

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