2-Chloro-1-(4-hydroxy-3-(1h-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1h-pyrazol-1-yl)ethan-1-one CAS 790263-76-2
| CAS No. | 790263-76-2 |
| Molecular Formula | C20H18ClN3O3 |
| Molecular Weight | 383.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-1-(4-hydroxy-3-(1h-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1h-pyrazol-1-yl)ethan-1-one.
2-Chloro-1-(4-hydroxy-3-(1h-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1h-pyrazol-1-yl)ethan-1-one (CAS 790263-76-2) is a high-purity analytical reference standard with the molecular formula C20H18ClN3O3 and a molecular weight of 383.83 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloro-1-(4-hydroxy-3-(1h-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1h-pyrazol-1-yl)ethan-1-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 383.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Chloro-1-(4-hydroxy-3-(1h-indol-3-yl)-5-(4-methoxyphenyl)-4,5-dihydro-1h-pyrazol-1-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H18ClN3O3 |
| Molecular Weight | 383.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Methyl 2-[(5-chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)formamido]-2-phenylacetate (CAS 1008999-57-2)
- 4-(5-Chloro-2-((4-fluorobenzyl)thio)pyrimidine-4-carboxamido)butanoic Acid (CAS 1225162-49-1)
- Methyl 5-chloro-4-({[(4-methylbenzyl)oxy]imino}methyl)-1-phenyl-1H-pyrazole-3-carboxylate (CAS 477709-62-9)
- 3-Chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(triisopropylsilyl)-1H-pyrrole (CAS 1126425-82-8)
- 2-[(2-Chloro-6-fluorophenyl)methyl]-4-[(1E)-[(1-phenylethyl)imino]methyl]benzene-1,3-diol (CAS 338750-15-5)
- 2-[(2-Chloro-6-fluorophenyl)methyl]-4-[(1E)-{[(4-methylphenyl)methyl]imino}methyl]benzene-1,3-diol (CAS 341967-46-2)
- 2-(4-((4-Chloro-2-nitrophenyl)sulfonyl)piperazin-1-yl)pyrimidine (CAS 866153-27-7)
- 1-(4-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)phenyl)ethan-1-one (CAS 338979-19-4)
Recommended Standards
- 2'-MeCCPA (CAS 205171-12-6)
- 5-[1-(3-Chlorobenzoyl)pyrrolidin-2-yl]-3-(4-methoxyphenyl)-1,2,4-oxadiazole (CAS 855129-92-9)
- 1-(4-Chlorophenyl)-N-(2-ethoxyphenyl)-6-methyl-4-oxo-1,4-dihydropyridazine-3-carboxamide (CAS 869875-89-8)
- Ethyl 2-(2-benzoylhydrazinyl)-5-(4-chlorophenyl)-1H-pyrrole-3-carboxylate (CAS 338419-67-3)
- O4-tert-butyl O2-methyl 5-methylthieno[3,2-b]pyrrole-2,4-dicarboxylate (CAS 2756784-04-8)
- 3-(difluoromethyl)-4,5-dihydro-1H-pyrazol-5-one (CAS 1339647-15-2)
- 3-morpholinopropylamine (CAS 123-00-2)
- Methyl 5-chloro-6-ethoxy-2-formylnicotinate (CAS 1779125-31-3)
- 1-(3-cyanophenyl)-1H-pyrazole-3-carboxylic acid (CAS 1803595-29-0)
- (2-Cyclopropoxy-3-nitrophenyl)(methyl)sulfane (CAS 1243321-01-8)
- 2-(3,5-Dichlorophenyl)acetonitrile (CAS 52516-37-7)
- Methyl 2-(ethylamino)-2-methyl-3-(1h-pyrazol-1-yl)propanoate (CAS 1251270-84-4)
- 3-Methyl-4-(3-(trifluoromethyl)phenoxy)isoxazolo[5,4-d]pyrimidine (CAS 551930-91-7)
- Semaglutide Impurity 5 (CAS 23406-82-8)
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