4-(Chlorosulfonyl)thiophene-2-carboxylic acid CAS 79279-54-2
| CAS No. | 79279-54-2 |
| Molecular Formula | C5H3ClO4S2 |
| Molecular Weight | 226.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 4-(Chlorosulfonyl)thiophene-2-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
4-(Chlorosulfonyl)thiophene-2-carboxylic acid (CAS 79279-54-2) is a high-purity analytical reference standard with the molecular formula C5H3ClO4S2 and a molecular weight of 226.66 g/mol.
Structurally, 4-(Chlorosulfonyl)thiophene-2-carboxylic acid (C5H3ClO4S2) contains a carbohydrate-derived structure, a sulfone group, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 226.66 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C5H3ClO4S2 |
| Molecular Weight | 226.66 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
Related Chlorosulfonyl Standards
- 5-(Chlorosulfonyl)thiophene-2-carboxylic acid (CAS 10216-12-3)
- 4-(Chlorosulfonyl)thiophene-3-carboxylic acid (CAS 1375472-54-0)
- 3-(Chlorosulfonyl)thiophene-2-carboxylic acid (CAS 741653-98-5)
- 5-(Chlorosulfonyl)thiophene-3-carboxylic acid (CAS 875163-07-8)
- 4-(Chlorosulfonyl)benzoic acid (CAS 10130-89-9)
- 3-[(chlorosulfonyl)(2-methoxyethyl)amino]propanenitrile (CAS 1343675-60-4)
- Ethyl 2-(1-(chlorosulfonyl)cyclopropyl)acetate (CAS 1461708-73-5)
- methyl 2-(chlorosulfonyl)cyclopentane-1-carboxylate (CAS 1552637-43-0)
Recommended Standards
- 4-(Allyloxy)-3-chloro-5-methoxybenzaldehyde (CAS 428479-97-4)
- 4-[(6-Chloropyridin-2-yl)carbonyl]morpholine (CAS 720693-08-3)
- 4-(allyloxy)-2-chloro-5-methoxybenZaldehyde (CAS 692279-00-8)
- 4-[(Chloroacetyl)amino]-N-methylbenzamide (CAS 871217-90-2)
- Thiosemicarbazide (CAS 79-19-6)
- 4-FLUORO-2-METHYL-1H-INDOLE-5-CARBONITRILE (CAS 1401727-02-3)
- 1-(2-Fluoro-4-methylpyridin-3-yl)ethanone (CAS 886364-66-5)
- 1-[1-(2-Dimethylamino-acetyl)-pyrrolidin-3-yl]-1H-pyrazole-4-carboxylic acid (CAS 1316219-85-8)
- 1-{(2R,3S)-4-[(4-Chloro-1,1,2,2,3,3,4,4-octafluorobutyl)sulfonyl]-5-methyl-3-phenyl-2,3-dihydro-2-furanyl}ethanone (CAS 771491-68-0)
- 2-(Bromomethyl)-3-chloro-5-fluoropyridine (CAS 1227586-53-9)
- N-(3-Fluorophenyl)-2-(4-methyl-6-oxo-2-(piperidin-1-yl)pyrimidin-1(6H)-yl)acetamide (CAS 1251559-57-5)
- Ethyl 1-(3-chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate (CAS 112055-35-3)
- 2-((Methylthio)methyl)piperidine (CAS 383127-99-9)
- Semaglutide-d8 Tetratrifluoroacetate (CAS CATO-C4X-222617)
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