Estriol EP Impurity G CAS 793-89-5
| CAS No. | 793-89-5 |
| Molecular Formula | C18H24O3 |
| Molecular Weight | 288.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 288.38 g/mol gives Estriol EP Impurity G distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Estriol EP Impurity G (CAS 793-89-5) is a certified pharmaceutical impurity reference standard with the molecular formula C18H24O3 and a molecular weight of 288.38 g/mol.
The molecular framework of Estriol EP Impurity G (C18H24O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Estriol EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H24O3 |
| Molecular Weight | 288.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Estriol Standards
Recommended Standards
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- Aluminum Borohydride (DISCONTINUED) (CAS 16962-07-5)
- 2-(3-(Benzyloxy)-6-bromo-2-fluorophenyl)-1,3-dioxolane (CAS 2379321-63-6)
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