6-chloro-3-(trifluoromethyl)pyridin-2-amine CAS 79456-27-2
| CAS No. | 79456-27-2 |
| Molecular Formula | C6H10ClF3N2 |
| Molecular Weight | 202.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-chloro-3-(trifluoromethyl)pyridin-2-amine is closely related to fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 6-chloro-3-(trifluoromethyl)pyridin-2-amine (CAS 79456-27-2), a certified reference material (molecular formula C6H10ClF3N2, MW 202.61 g/mol) for analytical method development and quality control.
Based on its molecular formula C6H10ClF3N2, 6-chloro-3-(trifluoromethyl)pyridin-2-amine contains fluorine/chlorine substitution; these features give the compound characteristic molecular-ion distribution patterns in mass spectrometry. The molecular weight of 202.61 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-chloro-3-(trifluoromethyl)pyridin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H10ClF3N2 |
| Molecular Weight | 202.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 5-chloro-3-(trifluoromethyl)pyridin-2-amine (CAS 79456-33-0)
- 6-Chloro-3-ethoxy-2-fluorobenzaldehyde (CAS 363620-21-7)
- 4-Ethoxy-3-fluorobenzoyl chloride (CAS 5710-32-7)
- 6-chloro-5-(trifluoromethyl)pyridin-2-amine (CAS 79456-28-3)
- ethyl 2-cyano-2-methyl-2-[(trimethylsilyl)oxy]acetate (CAS 67405-85-0)
- Xenon-<SUP>124</SUP>Xe (CAS 15687-60-2)
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- 5-[(2-chlorophenyl)amino]-1,3,4-thiadiazole-2-thiol (CAS 37844-22-7)
- N-(Thiazol-2-yl)-2-(thiophen-2-ylsulfonyl)acetamide (CAS 1021020-73-4)
- 1-(2,6-Dichlorophenyl)-1,3-dihydro-5-hydroxy-2H-indol-2-one (CAS 30267-40-4)
- (E)-3-(6-(1-Hydroxy-3-(pyrrolidin-1-yl)-1-(p-tolyl)propyl)pyridin-2-yl)acrylic Acid (CAS 93962-64-2)
- 7-(3-((tert-Butyldiphenylsilyl)oxy)propyl)-5H-pyrido[4,3-b]indole (CAS 2267291-20-1)
- (Asp28)-Exenatide trifluoroacetate salt (CAS 1678417-24-7)
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