2-Chloro-5-methylbenzotrifluoride CAS 80245-27-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-5-methylbenzotrifluoride.

2-Chloro-5-methylbenzotrifluoride (CAS 80245-27-8) is a high-purity analytical reference standard with the molecular formula C8H6ClF3 and a molecular weight of 194.58 g/mol.

Owing to fluorine/chlorine substitution, an aromatic ring system, 2-Chloro-5-methylbenzotrifluoride is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 194.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chloro-5-methylbenzotrifluoride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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