4-Methyl-3-nitrothiophen-2-amine CAS 80313-10-6
| CAS No. | 80313-10-6 |
| Molecular Formula | C5H6N2O2S |
| Molecular Weight | 158.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Methyl-3-nitrothiophen-2-amine is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-Methyl-3-nitrothiophen-2-amine (CAS 80313-10-6), molecular formula C5H6N2O2S and molecular weight 158.18 g/mol, is a CATO reference standard with documented purity and traceability.
4-Methyl-3-nitrothiophen-2-amine (C5H6N2O2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Methyl-3-nitrothiophen-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6N2O2S |
| Molecular Weight | 158.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Methyl Standards
- 5-Methyl-2-nitrothiophen-3-amine (CAS 1404364-31-3)
- (5-Nitrothiophen-2-yl)methanamine (CAS 90993-47-8)
- (4-Nitrothiophen-2-yl)methanol (CAS 20898-91-3)
- 2-(2-Nitrothiophen-3-yl)acetonitrile (CAS 93418-94-1)
- 1-(3-Nitrothiophen-2-yl)ethanone (CAS 65967-45-5)
- 1-(5-Nitrothiophen-3-yl)ethan-1-one (CAS 58157-89-4)
- 2-nitrothiophen-3-ol (CAS 128496-62-8)
- 2-(5-Nitrothiophen-2-yl)ethan-1-amine (CAS 926256-13-5)
Recommended Standards
- 4-Methyl-1,2,3-thiadiazole-5-carbohydrazide (CAS 75423-15-3)
- 4-Methyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazole-3-carboxamide (CAS 61320-82-9)
- 4-Methoxythiophene-3-carboxylic Acid (CAS 71050-40-3)
- 5-(Hydroxymethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (CAS 93185-31-0)
- N,N-Dimethyl-1-(6-nitro-3-pyridinyl)-4-piperidinamine (CAS 1002317-12-5)
- 2-((tert-Butoxycarbonyl)amino)-3-hydroxybenzoic acid (CAS 1397025-76-1)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (2-amino-4-cyclopropylpyrimidin-5-yl)boronate (CAS 2223031-78-3)
- 5-Amino-4-bromo-isoquinoline (CAS 16552-65-1)
- 7-(Difluoromethyl)indoline-2,3-dione (CAS 1344894-30-9)
- 6-(Benzyloxy)-2-chloroquinoline (CAS 623144-17-2)
- N-(4-Aminophenyl)-2-(2-ethoxyethoxy)benzamide (CAS 1020055-73-5)
- 5-(1-Hydroxypropylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 66696-76-2)
- Preptin (rat) trifluoroacetate salt (CAS 315197-73-0)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
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