4-Methoxythiophene-3-carboxylic Acid CAS 71050-40-3
| CAS No. | 71050-40-3 |
| Molecular Formula | C6H6O3S |
| Molecular Weight | 158.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Methoxythiophene-3-carboxylic Acid.
4-Methoxythiophene-3-carboxylic Acid (CAS 71050-40-3), molecular formula C6H6O3S and molecular weight 158.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Methoxythiophene-3-carboxylic Acid (C6H6O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Methoxythiophene-3-carboxylic Acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6O3S |
| Molecular Weight | 158.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1977 |
| Sulfur Atoms | 1 |
Related Methoxythiophene Standards
- 2-Methoxythiophene-3-carboxylic acid (CAS 71154-29-5)
- 3-Methoxythiophene-2-carboxylic acid (CAS 60166-83-8)
- 4-Methoxythiophene-2-carboxylic Acid (CAS 77133-27-8)
- 4-Methoxythiophene-2-boronic acid (CAS 1321901-82-9)
- 3-Methoxythiophene-2-boronic acid (CAS 162607-22-9)
- (E)-3-methoxythiophene-2-carbaldehyde oxime (CAS 1824827-05-5)
- 3-Methoxythiophene-2-carboxamide (CAS 78031-17-1)
- 4-Methoxythiophene-3-carboxamide (CAS 65369-29-1)
Recommended Standards
- 4-Methyl-1,2,3-thiadiazole-5-carbohydrazide (CAS 75423-15-3)
- 4-Mercapto-1H-imidazole-5-carbohydrazide (CAS 58413-35-7)
- 4-Methyl-3-nitrothiophen-2-amine (CAS 80313-10-6)
- 4-HYdroxy-thiophene-2-carboxylic acid methyl ester (CAS 5118-04-7)
- N6-Benzoyl-2'-o-methyl-adenosine (CAS 85079-00-1)
- 1,3-di-tert-butyl cyclohexane-1,3-dicarboxylate (CAS 220179-70-4)
- Ethyl 2-amino-3,6-dichlorobenzoate (CAS 1183349-06-5)
- 5-(4-Aminophenoxy)picolinic acid dihydrochloride (CAS 72133-30-3)
- Rimegepant Impurity 17 (CAS 1190363-50-8)
- Bortezomib(Trimeric Boroxine Form) (CAS 390800-88-1)
- (6-(tertButoxycarbonyl)-5,6,7,8-tetrahydro-1,6-naphthyridin-3-yl)boronic acid (CAS 2408429-82-1)
- 3-tert-Butyl-5-ethyltoluene (CAS 6630-01-9)
- 5-[4-(Propan-2-yl)phenyl]-5H-thieno[2,3-c]pyrrole (CAS 338977-11-0)
- Peptide WE-14 (CAS 115136-18-0)
Why CATO?
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