7,12-Dioxaspiro[5.6]Dodecan-3-one CAS 80427-20-9
| CAS No. | 80427-20-9 |
| Molecular Formula | C10H16O3 |
| Molecular Weight | 184.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 7,12-Dioxaspiro[5.6]Dodecan-3-one (CAS 80427-20-9), a certified reference material (molecular formula C10H16O3, MW 184.23 g/mol) for analytical method development and quality control.
The molecular framework of 7,12-Dioxaspiro[5.6]Dodecan-3-one (C10H16O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H16O3 |
| Molecular Weight | 184.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1979 |
Related Dioxaspiro Standards
- 2-{1,4-dioxaspiro[4.5]decan-8-yl}acetaldehyde (CAS 143948-97-4)
- 1-{1,4-Dioxaspiro[4.5]decan-6-yl}ethanone (CAS 16111-99-2)
- 1-(1,4-Dioxaspiro[4.5]decan-8-yl)ethan-1-one (CAS 35477-39-5)
- 2-{1,4-dioxaspiro[4.5]decan-6-yl}acetaldehyde (CAS 809233-15-6)
- 1,5-Dioxaspiro[5.5]undecane-2,4-dione (CAS 1658-27-1)
- 1,4-Dioxaspiro[4.5]decane-8-carboxamide (CAS 30482-24-7)
- (8-Methyl-1,4-dioxaspiro[4.5]Decan-8-yl)methanamine (CAS 1207111-64-5)
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Recommended Standards
- 6-Oxo-3-(prop-1-en-2-yl)heptanoic Acid (CAS 4436-82-2)
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- 7-methoxyisochroman-4-one (CAS 54212-34-9)
- n-(3-Nitrophenyl)-n-(phenylsulfonyl)benzenesulfonamide (CAS 1114824-00-8)
- (R)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate (CAS 23788-74-1)
- 1-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)piperidin-4-amine (CAS 1525554-57-7)
- 4-Fluoro-4-phenylpiperidine (CAS 400770-91-4)
- 2,4-Bis(trifluoromethyl)cinnamic acid (CAS 773129-10-5)
- 2-Methyl-6-nitro-1H-benzo[d]imidazol-1-ol (CAS 405314-01-4)
- 2-(4'-Bromo-[1,1'-biphenyl]-4-yl)-2-methyl-1,3-dioxolane (CAS 107967-74-8)
- 1-(2-Aminoethyl)-6-(ethylthio)-N-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1105197-82-7)
- 1-(2-Chlorobenzyl)-1H-imidazole-5-carboxylic acid (CAS 1439899-35-0)
- Insulin Degludec Impurity 14 (CAS CATO-C4X-215714)
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