Tetrahydro-1H-pyrrolizine-7a(5H)-methanamine Dihydrochloride CAS 80842-67-7
| CAS No. | 80842-67-7 |
| Molecular Formula | C8H16N2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies Tetrahydro-1H-pyrrolizine-7a(5H)-methanamine Dihydrochloride (CAS 80842-67-7), a certified reference material (molecular formula C8H16N2HCl, MW 176.69 g/mol) for analytical method development and quality control.
The molecular framework of Tetrahydro-1H-pyrrolizine-7a(5H)-methanamine Dihydrochloride (C8H16N2HCl) is characterized by chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H16N2 2*HCl |
| Molecular Weight | 176.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- (5-chloro-3-methyl-pyrazin-2-yl)methanol (CAS 2170456-86-5)
- (2R,3S,5R)-5-(2-Allyl-6-amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol (CAS 76713-12-7)
- rel-(1R,2S)-Cyclohexa-3,5-diene-1,2-diol (CAS 17793-95-2)
- 2-Hydrazinyl-4-(naphthalen-2-yl)pyrimidine (CAS 932240-75-0)
- 6-Bromo-7-fluoro-3h-1,3-benzothiazole-2-thione (CAS 2306264-34-4)
- 2-[(2-Hydroxyethyl)amino]benzonitrile (CAS 175666-56-5)
- Epalrestat Impurity 61 (CAS CATO-C4X-223661)
- Relugolix Impurity 63 (CAS CATO-C4X-242963)
- Valsartan Impurity 96 (CAS CATO-C4X-105796)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
Why CATO?
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