1-((2-(4-Chlorophenyl)-2-Methylpropoxy)Methyl)-3-(2-Fluorophenoxy)Benzene CAS 80843-66-9
| CAS No. | 80843-66-9 |
| Molecular Formula | C23H22ClFO2 |
| Molecular Weight | 384.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-((2-(4-Chlorophenyl)-2-Methylpropoxy)Methyl)-3-(2-Fluorophenoxy)Benzene.
1-((2-(4-Chlorophenyl)-2-Methylpropoxy)Methyl)-3-(2-Fluorophenoxy)Benzene (CAS 80843-66-9) is a high-purity analytical reference standard with the molecular formula C23H22ClFO2 and a molecular weight of 384.87 g/mol.
The molecular framework of 1-((2-(4-Chlorophenyl)-2-Methylpropoxy)Methyl)-3-(2-Fluorophenoxy)Benzene (C23H22ClFO2) is characterized by a steroid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H22ClFO2 |
| Molecular Weight | 384.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F/Cl-containing |
Related Chlorophenyl Standards
- 1-((2-(4-Chlorophenyl)-2-Methylpropoxy)Methyl)-3-(4-Fluorophenoxy)Benzene (CAS 80843-60-3)
- (E)-3-(3-chlorophenyl)-N-(2-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)(methyl)amino)-2-oxoethyl)acrylamide (CAS 1550008-55-3)
- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino 4-methylbenzoate (CAS 477872-47-2)
- [(3Z)-1-[(4-Chlorophenyl)methyl]-5-methyl-2-oxo-2,3-dihydro-1H-indol-3-ylidene]amino pentanoate (CAS 320420-87-9)
- {2-[(4-chlorophenyl)sulfanyl]pyridin-3-yl}methyl N-(2-methylphenyl)carbamate (CAS 338413-64-2)
- 1-(4-Chlorophenyl)-3-(5-Isopropyl-1-Methyl-3-Oxo-2-Phenyl-2,3-Dihydro-1H-Pyrazol-4-Yl)Urea (CAS 903895-98-7)
- 2-[(4-Chlorophenyl)sulfanyl]-N-[(4-methoxyphenyl)methyl]pyridine-3-carboxamide (CAS 866153-85-7)
- 5-(3-Chlorophenyl)-7-phenyltetrahydro-3H-pyrrolo[3',4':3,4]pyrrolo[1,2-c]thiazole-6,8(1H,7H)-dione (CAS 321521-97-5)
Recommended Standards
- 4-Bromo-2,3,7,8-tetrachlorodibenzo[b,d]furan (CAS 115656-08-1)
- 1-Bromo-2,3,7,8-tetrachlorodibenzo[b,d]furan (CAS 104549-43-1)
- Amodiaquine Impurity 9 (CAS CATO-C4X-24719)
- N-(3-(((Benzyloxy)imino)methyl)-4-chlorophenyl)-2-methylfuran-3-carbothioamide (CAS 178870-45-6)
- (S)-1-(3,4-dibromophenyl)butan-1-amine (CAS 1213202-39-1)
- tert-Butyl ((5-(trifluoromethyl)pyrimidin-2-yl)methyl)carbamate (CAS 1240597-19-6)
- (R)-2-amino-3-(1-(tert-butoxycarbonyl)-1H-indol-5-yl)propanoic acid (CAS 2387566-81-4)
- Racemic-(3R,3aR,7aR)-tert-butyl 3-(((benzyloxy)carbonyl)amino)hexahydropyrano[3,2-b]pyrrole-1(2H)-carboxylate (CAS 1341039-68-6)
- Sodium DL-Lactate-2,3,3,3-d4 (60% w/w in H2O) (CAS 344299-52-1)
- 2,2,3,3-Tetramethylcyclopropan-1-amine hydrochloride (CAS 1269455-96-0)
- N-(6-morpholinopyridin-3-yl)-4-(trifluoromethyl)benzamide (CAS 383146-25-6)
- 1-(3,4-Diaminophenyl)ethan-1-one (CAS 21304-39-2)
- 3-Amino-6-(propan-2-yl)-N-[4-(trifluoromethoxy)phenyl]-5H,6H,7H,8H-thieno[2,3-b]1,6-naphthyridine-2-carboxamide (CAS 728025-83-0)
- Hexapeptide-11 (CAS 100684-36-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com