6-Chloropyrimidin-2(1H)-one·xhydrate CAS 80927-55-5
| CAS No. | 80927-55-5 |
| Molecular Formula | C4H3ClN2O |
| Molecular Weight | 130.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloropyrimidin-2(1H)-one·xhydrate.
6-Chloropyrimidin-2(1H)-one·xhydrate (CAS 80927-55-5), molecular formula C4H3ClN2O and molecular weight 130.53 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-Chloropyrimidin-2(1H)-one·xhydrate (C4H3ClN2O) is characterized by an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloropyrimidin-2(1H)-one·xhydrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H3ClN2O |
| Molecular Weight | 130.53 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloropyrimidin Standards
- 4-Chloropyrimidin-5-ol (CAS 1261536-41-7)
- 5-Chloropyrimidin-2-ol (CAS 214290-50-3)
- 2-chloropyrimidin-5-amine (CAS 56621-90-0)
- 4-chloropyrimidin-5-amine (CAS 54660-78-5)
- (2-Chloropyrimidin-4-yl)methanamine (CAS 181363-10-0)
- (2-Chloropyrimidin-5-yl)methanamine (CAS 933685-83-7)
- (4-Chloropyrimidin-2-yl)methanamine (CAS 944902-16-3)
- (6-Chloropyrimidin-4-yl)methanamine (CAS 933702-18-2)
Recommended Standards
- 2-Furoyl chloride (CAS 527-69-5)
- 6-Chloro-3(2H)-pyridazinone (CAS 19064-67-6)
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- Pazopanib Impurity 26 (CAS 55873-09-1)
- 2-Cyclohexylbut-3-yn-2-ol (CAS 825-16-1)
- 4-BEC Hydrochloride (1.0mg/ml in Acetonitrile) (CAS 135333-26-5)
- 4-Bromo-5-chloro-2-methylbenzonitrile (CAS 1228376-18-8)
- 4-MONOIODOFLUORESCEIN,DISODIUM SALT (CAS 52010-86-3)
- Quinoline N-Oxide (CAS 1613-37-2)
- Methyl (R)-2-aminopent-4-enoate (CAS 81136-73-4)
- 2-(Prop-2-en-1-ylsulfanyl)-1h-1,3-benzodiazole (CAS 51389-04-9)
- 2-Methylthiomorpholine 1-oxide (hydrochloride) (CAS 2792200-49-6)
- Ethosuximide impurity 19 (CAS CATO-C4X-262519)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com