(6-Chloropyrimidin-4-yl)methanamine CAS 933702-18-2
| CAS No. | 933702-18-2 |
| Molecular Formula | C5H6ClN3 |
| Molecular Weight | 143.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (6-Chloropyrimidin-4-yl)methanamine.
(6-Chloropyrimidin-4-yl)methanamine (CAS 933702-18-2), molecular formula C5H6ClN3 and molecular weight 143.57 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (6-Chloropyrimidin-4-yl)methanamine (C5H6ClN3) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H6ClN3 |
| Molecular Weight | 143.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyrimidin Standards
- (2-Chloropyrimidin-4-yl)methanamine (CAS 181363-10-0)
- (2-Chloropyrimidin-5-yl)methanamine (CAS 933685-83-7)
- (4-Chloropyrimidin-2-yl)methanamine (CAS 944902-16-3)
- C-(5-Chloropyrimidin-2-yl)methylamine (CAS 426266-77-5)
- (4-Chloropyrimidin-2-yl)methanol (CAS 1093880-89-7)
- (5-Chloropyrimidin-4-yl)hydrazine (CAS 122082-97-7)
- (4-Chloropyrimidin-5-yl)methanol (CAS 389799-45-5)
- (6-chloropyrimidin-4-yl)methanol (CAS 1025351-41-0)
Recommended Standards
- (6-chloropyridazin-3-yl)methanamine (CAS 871826-15-2)
- 1-(4-Chloro-1H-pyrrol-2-yl)ethan-1-one (CAS 51333-63-2)
- (6-Chloro-2-pyridinyl)methanol (CAS 33674-97-4)
- 1-Methyl-1H-pyrrole-2-carbonyl chloride (CAS 26214-68-6)
- Ethyl 3,4-dichloroisothiazole-5-carboxylate (CAS 69376-25-6)
- 5-Methyl-1-(4-oxo-3,4,5,6,7,8-hexahydroquinazolin-2-yl)-1H-pyrazole-4-carboxylic acid (CAS 1177204-21-5)
- 2-Amino-N-ethyl-N-(3-nitrobenzyl)acetamide (CAS 1353982-47-4)
- 6-Chloro-5-methoxy-3-methyl-1H-indole (CAS 172170-01-3)
- 1,2,5-Trimethylpyrrolidine-2,5-dicarbonitrile (CAS 57013-16-8)
- 2-((5-Chloro-7-iodoquinolin-8-yl)oxy)-N-hydroxyacetimidamide (CAS 88757-18-0)
- tert-Butyl (S)-4-(2-(((benzyloxy)carbonyl)amino)-3-methoxy-3-oxopropyl)piperidine-1-carboxylate (CAS 195877-54-4)
- 4-Amino-2-fluoro-5-iodobenzonitrile (CAS 380241-60-1)
- 6-Methoxy-2-methylpyridine-3-boronic Acid (CAS 459856-12-3)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
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