(3-(2-Iodophenyl)-1H-indol-1-yl)(phenyl)methanone CAS 809274-68-8

Purity 97%+In StockPharmaceutical Standards
CAS No.809274-68-8
Molecular FormulaC21H14INO
Molecular Weight423.25 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3-(2-Iodophenyl)-1H-indol-1-yl)(phenyl)methanone CAS 809274-68-8 chemical structure

Description

The molecular framework of (3-(2-Iodophenyl)-1H-indol-1-yl)(phenyl)methanone (C21H14INO) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

(3-(2-Iodophenyl)-1H-indol-1-yl)(phenyl)methanone (CAS 809274-68-8), molecular formula C21H14INO and molecular weight 423.25 g/mol, is a CATO reference standard with documented purity and traceability.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC21H14INO
Molecular Weight423.25 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentI-containing
Nitrogen Atoms1

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