Dimethyl 2-(3-(trifluoromethyl)pyridin-2-yl)malonate CAS 809276-86-6
| CAS No. | 809276-86-6 |
| Molecular Formula | C11H10F3NO4 |
| Molecular Weight | 277.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 277.20 g/mol gives Dimethyl 2-(3-(trifluoromethyl)pyridin-2-yl)malonate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Dimethyl 2-(3-(trifluoromethyl)pyridin-2-yl)malonate (CAS 809276-86-6), molecular formula C11H10F3NO4 and molecular weight 277.20 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H10F3NO4, Dimethyl 2-(3-(trifluoromethyl)pyridin-2-yl)malonate contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 277.20 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H10F3NO4 |
| Molecular Weight | 277.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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- Glycolic acid ethoxy acid 4-tert-butylphenyl ether (CAS 104909-82-2)
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