5-(4-Chlorophenyl)-3-(methylthio)-1H-pyrazole CAS 80967-20-0
| CAS No. | 80967-20-0 |
| Molecular Formula | C10H9ClN2S |
| Molecular Weight | 224.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
5-(4-Chlorophenyl)-3-(methylthio)-1H-pyrazole (CAS 80967-20-0), molecular formula C10H9ClN2S and molecular weight 224.71 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution, 5-(4-Chlorophenyl)-3-(methylthio)-1H-pyrazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 224.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H9ClN2S |
| Molecular Weight | 224.71 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 4-(3-Chlorophenyl)-2-methylthiazol-5-amine (CAS 1247687-32-6)
- (S)-2-(2-Chlorophenyl)-2,5-dihydrothiophene-3-carbaldehyde (CAS 1255188-94-3)
- (R)-2-(3-Chlorophenyl)-2,5-dihydrothiophene-3-carbaldehyde (CAS 1255188-96-5)
- (R)-2-(4-Chlorophenyl)-2,5-dihydrothiophene-3-carbaldehyde (CAS 1255188-99-8)
- 5-(4-Chlorophenyl)-1-methyl-1H-imidazole-2-thiol (CAS 17452-31-2)
- (2-(2-Chlorophenyl)thiazol-4-yl)methanamine (CAS 885280-09-1)
- (2-(3-Chlorophenyl)thiazol-4-yl)methanamine (CAS 775579-08-3)
- (2-(4-Chlorophenyl)thiazol-4-yl)methanamine (CAS 772338-96-2)
Recommended Standards
- 5-(2-Chloro-benzyl)-thiazol-2-ylamine (CAS 207463-32-9)
- 5-[(3-chlorophenyl)methyl]-1,3-thiazol-2-amine (CAS 313960-06-4)
- 4-Chloro-N-(p-tolyl)thiazol-2-amine (CAS 912969-57-4)
- 5-[(4-Chlorophenyl)methyl]-1,3-thiazol-2-amine (CAS 290835-51-7)
- 2-(5-(2-Fluorophenyl)-4-nitro-1H-pyrazol-1-yl)ethanol (CAS 1708380-56-6)
- N1-((2-Bromopyridin-4-yl)methyl)-N1-isopropylethane-1,2-diamine (CAS 1353960-30-1)
- 4-tert-Butyl-1-cyclohexanecarboxylic anhydride (CAS 25774-37-2)
- N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-N-(4-chlorobenzyl)-1,1,1-trifluoromethanesulfonamide (CAS 321432-42-2)
- 3-Bromo-N-(2H-tetrazol-5-yl)benzamide (CAS 344896-75-9)
- 2-Amino-3-(1-ethyl-1h-1,2,4-triazol-5-yl)propan-1-ol (CAS 1493088-78-0)
- Rosuvastatin EP Impurity L Calcium(Mixture of Diastereomers) (CAS 1024064-70-7)
- 1779120-18-1 2-Bromo-4-(thiazolidin-3-yl)nitrobenzene (CAS 1779120-18-1)
- Lemborexant Impurity 97 (CAS CATO-C4X-304297)
- Semaglutide Impurity 128 (CAS 2490269-78-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com