Ranitidine Hydrochloride EP Impurity F CAS 81074-81-9
| CAS No. | 81074-81-9 |
| Molecular Formula | C8H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Ranitidine Hydrochloride EP Impurity F (CAS 81074-81-9) is a certified pharmaceutical impurity reference standard with the molecular formula C8H13NO2HCl and a molecular weight of 191.66 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Ranitidine Hydrochloride EP Impurity F is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 191.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Ranitidine Hydrochloride EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H13NO2 HCl |
| Molecular Weight | 191.66 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Ranitidine Standards
- Ranitidine Impurity 11 (CAS 102721-76-6)
- Ranitidine Impurity 13 (CAS 112233-24-6)
- Ranitidine Impurity 21 (CAS 112233-25-7)
- Ranitidine Impurity 10 (CAS 113224-25-2)
- Ranitidine EP Impurity D (CAS 117846-02-3)
- Ranitidine N,S-Dioxide (CAS 1185237-42-6)
- Ranitidine-d6 HCl (CAS 1185238-09-8)
- Ranitidine-D6 (CAS 1185514-83-3)
Recommended Standards
- Palbociclib Impurity 98 (CAS 2340184-77-0)
- Mirogabalin Impurity 4 (CAS 344428-05-3)
- Relebactam Impurity 44 (CAS CATO-C4X-214444)
- Ethyl (3Z,6Z,9Z,12Z,15Z,18Z)-3,6,9,12,15,18-heneicosahexaenoate (CAS 219731-94-9)
- Tert-butyl 4-(4-chlorothieno[3,2-d]pyrimidin-6-yl)-3,6-dihydropyridine-1(2H)-carboxylate (CAS 1574389-24-4)
- Paliperidone Impurity 95 HCl (CAS CATO-C4X-172495)
- (4-Bromo-5-fluoropyridin-2-yl)methanol (CAS 1805936-35-9)
- N-[2-(4-Isopropylphenoxy)propyl]-3-(tetrahydro-2-furanylmethoxy)aniline (CAS 1040681-59-1)
- 6-Chloro-n4-(tetrahydro-2h-thiopyran-3-yl)pyrimidine-2,4-diamine (CAS 1384790-17-3)
- Peptide 46 (H-4054.0500) (CAS 192122-40-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com