Ranitidine Impurity 21 CAS 112233-25-7
| CAS No. | 112233-25-7 |
| Molecular Formula | C21H33N5O4S |
| Molecular Weight | 451.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Ranitidine Impurity 21 (CAS 112233-25-7, C21H33N5O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Ranitidine Impurity 21 (C21H33N5O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Ranitidine Impurity 21 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H33N5O4S |
| Molecular Weight | 451.58 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Ranitidine Standards
- Ranitidine Impurity 12 (CAS CATO-C4X-137012)
- Ranitidine EP Impurity A (CAS 72126-78-4)
- Ranitidine EP Impurity J (CAS 1331637-48-9)
- Ranitidine N,S-Dioxide (CAS 1185237-42-6)
- Ranitidine Impurity 1 (CAS 72115-14-1)
- Ranitidine EP Impurity C (CAS 73851-70-4)
- Ranitidine EP Impurity E (CAS 73857-20-2)
- Ranitidine Impurity 28 (CAS CATO-C4X-137028)
Recommended Standards
- Phenoxymethylpenicillin Impurity 18 (CAS CATO-C4X-212618)
- Brexpiprazole impurity 125 (CAS CATO-C4X-1131125)
- Naratriptan Impurity 2 (CAS 2144776-32-7)
- For-met-leu-phe-ome (CAS 65929-03-5)
- Bromfenac Impurity 3 (CAS 1391052-54-2)
- Mosapride Impurity 53 (CAS CATO-C4X-104453)
- Iguratimod Impurity 30 (CAS CATO-C4X-182630)
- 2-[(Furan-2-ylmethyl)-amino]-N-p-tolyl-acetamide (CAS 332375-74-3)
- 4-Methoxy-3-methylpyridine 1-oxide (CAS 26883-29-4)
- 1-(2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-4-methylpiperazine (CAS 1092563-58-0)
- 4'-Difluoromethoxy-2,4-dichloro-2'-trifluoromethyl-biphenyl (CAS 1361851-01-5)
- GSK-3008348, >98% (HPLC) (CAS 1629249-33-7)
- 2-(chloromethyl)-5-methyl-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine dihydrochloride (CAS 1955548-55-6)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com