9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J CAS 813452-18-5

Purity 97%+In StockPharmaceutical Standards
CAS No.813452-18-5
Molecular FormulaC20H28FN3O3
Molecular Weight377.45 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

9Z723VGH7J
813452-18-5
Carmegliptin [USAN:INN]
2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)-
(4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one
Carmegliptin
R1579
RO4876904
UNII-9Z723VGH7J CAS 813452-18-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J.

9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J (CAS 813452-18-5), molecular formula C20H28FN3O3 and molecular weight 377.45 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 377.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

As a certified reference material (CRM), 9Z723VGH7J 813452-18-5 Carmegliptin [USAN:INN] 2-Pyrrolidinone, 1-((2S,3S,11bS)-2-amino-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo(a)quinolizin-3-yl)-4-(fluoromethyl)-, (4S)- (4S)-1-((2S,3S,11bS)-2-Amino-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido(2,1-a)isoquinolin-3-yl)-4-(fluoromethyl)pyrrolidin-2-one Carmegliptin R1579 RO4876904 UNII-9Z723VGH7J meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC20H28FN3O3
Molecular Weight377.45 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF-containing
Nitrogen Atoms3

Recommended Standards

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