Fmoc-His(1-Boc)-OH CAS 81379-52-4

Purity >95%In StockPharmaceutical Standards
CAS No.81379-52-4
Molecular FormulaC26H27N3O6
Molecular Weight477.51 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Fmoc-His(1-Boc)-OH CAS 81379-52-4 chemical structure

Description

The occurrence of Fmoc-His(1-Boc)-OH is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Fmoc-His(1-Boc)-OH (CAS 81379-52-4), molecular formula C26H27N3O6 and molecular weight 477.51 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, Fmoc-His(1-Boc)-OH is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 477.51 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), Fmoc-His(1-Boc)-OH meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC26H27N3O6
Molecular Weight477.51 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Nitrogen Atoms3

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