Guanosine-5-O-(1-thiotriphosphate) CAS 81570-50-5
| CAS No. | 81570-50-5 |
| Molecular Formula | C10H16N5O13P3S |
| Molecular Weight | 539.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Guanosine-5-O-(1-thiotriphosphate).
Guanosine-5-O-(1-thiotriphosphate) (CAS 81570-50-5) is a high-purity analytical reference standard with the molecular formula C10H16N5O13P3S and a molecular weight of 539.25 g/mol.
Based on its molecular formula C10H16N5O13P3S, Guanosine-5-O-(1-thiotriphosphate) contains a carbohydrate-derived structure, an amide group, a sulfone group, a phosphate ester group; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 539.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Guanosine-5-O-(1-thiotriphosphate) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H16N5O13P3S |
| Molecular Weight | 539.25 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Guanosine Standards
- Guanosine 3,5-cyclic Monophosphorothioate, β-Phenyl-1,N2-etheno-8-bromo-, Rp-Isomer, Sodium Salt - CAS 172806-20-1 - Calbiochem (CAS 172806-20-1)
- Guanosine 5'-TriphosphateDISCONTINUED (CAS 86-01-1)
- 160385-87-5 guanosine,8-[(4-chlorophenyl)thio]-, cyclic 3',5'-[(s)-hydrogen phosphorothioate] (9ci) (CAS 160385-87-5)
- Guanosine Impurity 6 (CAS 18186-48-6)
- Guanosine 3'-(trihydrogen diphosphate), 5'-(trihydrogen diphosphate) (CAS 32452-17-8)
- Guanosine Impurity 3 (CAS 117723-13-4)
- Guanosine 5'-Diphosphate (CAS 146-91-8)
- Guanosine Impurity 1 (CAS 69281-33-0)
Recommended Standards
- Gtp-γ-s (CAS 37589-80-3)
- N-Benzyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,7-Pentadecafluoroheptane-1-Sulphonamide (CAS 68298-10-2)
- 6-Thioguanosine Triphosphate (CAS 17670-19-8)
- 5-(4-(Bis(4-bromophenyl)amino)styryl)thiophene-2-carbaldehyde (CAS 1190764-15-8)
- 3-(5-Fluoropyridin-3-yl)propanoic acid (CAS 22620-28-6)
- n-((5-Bromothiophen-3-yl)methyl)-1-(methylsulfonyl)piperidin-4-amine (CAS 1154111-64-4)
- (2-Amino-6-fluoropyridin-4-yl)boronic acid (CAS 1214879-87-4)
- 1-(7-Amino-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-phenylethan-1-one (CAS 886494-72-0)
- 3-Phenylacrylimidamide (CAS 55978-61-5)
- N-(4-((4-Fluorobenzamido)methyl)phenyl)-N-methylmorpholine-4-carboxamide (CAS 1956390-03-6)
- 2-Chloro-6-methylpyrimidine-4-carbaldehyde (CAS 933720-98-0)
- 2-Bromo-6-chloropyrazolo[1,5-a]pyridine (CAS 886222-08-8)
- Diindeno[7,1-de:1′,7′-fg][1,3,2]dioxaphosphocin, 10,11,12,13-tetrahydro-5-hydroxy-3,7-bis[2,4,6-tris(1-methylethyl)phenyl]-, 5-oxide (CAS 2171300-28-8)
- Semaglutide impurity 78 (CAS CATO-C4X-222678)
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