Vilazodone Impurity 02 CAS 816438-46-7
| CAS No. | 816438-46-7 |
| Molecular Formula | C13H15ClN2 |
| Molecular Weight | 234.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 234.72 g/mol gives Vilazodone Impurity 02 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Vilazodone Impurity 02 (CAS 816438-46-7) is a certified pharmaceutical impurity reference standard with the molecular formula C13H15ClN2 and a molecular weight of 234.72 g/mol.
The molecular framework of Vilazodone Impurity 02 (C13H15ClN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Vilazodone Impurity 02 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H15ClN2 |
| Molecular Weight | 234.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Vilazodone Standards
- Vilazodone impurity 18 (CAS CATO-C4X-135518)
- Vilazodone Nitroso Impurity 7 (CAS 1000399-11-0)
- Vilazodone Intermidiate (CAS 183288-46-2)
- Vilazodone Impurity 6 (CAS 183288-47-3)
- Vilazodone Impurity 30 (CAS 276863-95-7)
- Vilazodone Impurity 6 (CAS 1451194-34-5)
- Vilazodone Impurity 7 (CAS 914927-40-5)
- Vilazodone Impurity 13 (CAS 1186225-86-4)
Recommended Standards
- UB 165 Fumarate (CAS 200432-86-6)
- 62443-89-4 Propanoic acid, 2-(4-chloro-3-methylphenoxy)-2-methyl- BRN 2526489 2-(4-Chloro-3-methylphenoxy)-2-methylpropanoic acid (CAS 62443-89-4)
- tert-Butyl 3-(2-chloroethyl)tetrahydrofuran-3-carboxylate (CAS 2137895-24-8)
- 5-chloro-1-isopropyl-7-methoxy-pyrazolo[4,3-d]pyrimidine (CAS 2445846-16-0)
- Edoxaban Impurity 33 (CAS 349125-14-0)
- Mirogabalin Impurity 12 (CAS CATO-C4X-292412)
- Vinpocetine Impurity 1 (CAS 77549-94-1)
- 4-(((6-Aminopyrido[2,3-b]pyrazin-8-yl)amino)methyl)benzenesulfonamide (CAS 21271-87-4)
- 4-Acetamido-2,2,6,6-tetramethylpiperidine (CAS 40908-37-0)
- tert-Butyl 4-(4-aminobenzyl)piperidine-1-carboxylate (CAS 221532-96-3)
- 1-(1,3-benzothiazol-6-yl)ethan-1-one (CAS 19989-35-6)
- Ethyl 6-oxo-5,6-dihydropyrazine-2-carboxylate (CAS 1286744-23-7)
- Mianserin Impurity 93 (CAS CATO-C4X-136993)
- Hexapeptide-9 (CAS 1228371-11-6)
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