6-Chloro-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde CAS 81933-74-6
| CAS No. | 81933-74-6 |
| Molecular Formula | C13H8ClN3O |
| Molecular Weight | 257.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
6-Chloro-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde (CAS 81933-74-6), molecular formula C13H8ClN3O and molecular weight 257.68 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 6-Chloro-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde (C13H8ClN3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 257.68 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 6-Chloro-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H8ClN3O |
| Molecular Weight | 257.68 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-4-phenylpyrido[2,3-b]pyrazin-3(4H)-one (CAS 1334103-17-1)
- 4-Chloro-6-(4-methylpiperazin-1-yl)-5-nitropyrimidine (CAS 154418-73-2)
- 4-Chloro-2-phenylpyrazolo[1,5-a]pyrazine-3-carbaldehyde (CAS 1707668-15-2)
- 2-Chloro-4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyrimidine (CAS 1956341-36-8)
- 2-Chloro-5-nitro-6-(piperidin-1-yl)pyrimidin-4-amine (CAS 405920-69-6)
- 3-Chloro-2-phenyl-2H-pyrazolo[4,3-c]pyridine-7-carbaldehyde (CAS 62176-73-2)
- 3-Chloro-6-(oxolan-2-ylmethoxy)pyridine-2-carboxylic acid (CAS 1021077-51-9)
- 2-Chloro-4-(4-fluorophenyl)quinoline (CAS 105189-21-7)
Recommended Standards
- 5-(2-Chlorophenyl)-3-(pyridin-4-yl)-1,2,4-oxadiazole (CAS 27199-40-2)
- 5-(2-Chlorophenyl)-3-(pyridin-2-yl)-1,2,4-oxadiazole (CAS 27199-42-4)
- 4-(2-Methyloxazol-4-yl)benzenesulfonyl chloride (CAS 1086376-81-9)
- n-{2-[4-(2-chloroacetyl)-2-fluorophenyl]ethyl}acetamide (CAS 1087784-55-1)
- AT 265 (CAS 66522-52-9)
- 3-Bromo-4-iodopyridine (CAS 89167-19-1)
- 4-[methyl(propan-2-yl)amino]benzoic acid hydrochloride (CAS 1235439-72-1)
- CAS 927816-03-3 (CAS 927816-03-3)
- 6-Chloro-2-(4-methoxyphenyl)quinoline-4-carbonyl chloride (CAS 1160263-31-9)
- 4-(2-(Benzyloxy)phenyl)-1H-pyrrole-3-carbonitrile (CAS 87388-24-7)
- Benzyl 2-{[(benzyloxy)carbonyl]amino}-2-(dimethoxyphosphoryl)acetate (CAS 898530-63-7)
- 2-((4-Aminobutyl)thio)ethyl pyrimidine-5-carboxylate (CAS 116218-70-3)
- 2-Amino-9-((2-hydroxyethoxy)methyl)-7H-purin-8(9H)-one (CAS 91503-60-5)
- Ephrin-A2-Selective YSA-Peptide (CAS 532441-10-4)
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