(2S,4R)-4-phenylpyrrolidine-2-carboxylic acid hydrochloride CAS 82087-67-0
| CAS No. | 82087-67-0 |
| Molecular Formula | C11H13NO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), (2S,4R)-4-phenylpyrrolidine-2-carboxylic acid hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies (2S,4R)-4-phenylpyrrolidine-2-carboxylic acid hydrochloride (CAS 82087-67-0), a certified reference material (molecular formula C11H13NO2HCl, MW 227.69 g/mol) for analytical method development and quality control.
The molecular framework of (2S,4R)-4-phenylpyrrolidine-2-carboxylic acid hydrochloride (C11H13NO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H13NO2 HCl |
| Molecular Weight | 227.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 5-Bromo-2-butoxybenzyl alcohol (CAS 831212-02-3)
- (2-Chloroethoxy)benzene .beta.-Chlorophenetole .beta.-Phenoxyethyl chloride 1-Phenoxy-2-chloroethane 2-Chloroethyl phenyl ether 2-Phenoxyethyl chloride 622-86-6 Benzene, (2-chloroethoxy)- Ether, 2-chloroethyl phenyl NSC-1073 NSC1073 Phenetole, .beta.-chloro- (CAS 622-86-6)
- WAY-352563 (CAS 505051-04-7)
- Pyrazine-2-carboximidohydrazine (CAS 18107-03-4)
- Sulfasalazine EP Impurity C (CAS 66030-25-9)
- 3-(Pyridin-3-yl)oxetan-3-amine (CAS 1393531-98-0)
- 2-Benzyl-3-bromo-2H-indazole (CAS 1414958-39-6)
- Ethyl (4-(2-((3,4-dimethylphenyl)amino)-2-oxoethyl)thiazol-2-yl)carbamate (CAS 946236-81-3)
- Goniotriol (CAS 96405-62-8)
- Tirzepatide Impurity 14 (CAS CATO-C4X-324014)
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