Sulfasalazine EP Impurity C CAS 66030-25-9
| CAS No. | 66030-25-9 |
| Molecular Formula | C18H14N4O3 |
| Molecular Weight | 334.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Sulfasalazine EP Impurity C (CAS 66030-25-9) is a certified pharmaceutical impurity reference standard with the molecular formula C18H14N4O3 and a molecular weight of 334.33 g/mol.
The molecular framework of Sulfasalazine EP Impurity C (C18H14N4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H14N4O3 |
| Molecular Weight | 334.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 4 |
Related Sulfasalazine Standards
- Sulfasalazine Impurity 20 (CAS CATO-C4X-141920)
- Sulfasalazine Impurity 27 (CAS 501111-03-1)
- Sulfasalazine EP Impurity I (CAS 21542-82-5)
- Sulfasalazine EP Impurity I (CAS 1310803-27-0)
- Sulfasalazine Impurity 2 (RRT 0.75) (CAS 139-56-0)
- Sulfasalazine Impurity 14 (CAS 330833-91-5)
- Sulfasalazine EP Impurity D (CAS 66364-70-3)
- Sulfasalazine Impurity 24 (CAS 409357-24-0)
Recommended Standards
- Ilaprazole Impurity 59 (CAS 1508282-87-8)
- Granisetron EP Impurity I (CAS 1363173-34-5)
- Ilaprazole Impurity 49（碘盐C4X-1130124更便宜） (CAS CATO-C4X-113049)
- 2-Np-Amoz (CAS 183193-59-1)
- Mianserin Impurity 93 (CAS CATO-C4X-136993)
- Efinaconazole impurity 51 (CAS CATO-C4X-124351)
- Proparacaine Impurity 19 (CAS 343773-15-9)
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- 4-Pyridoxic Acid-d3 (CAS 1435934-03-4)
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- 1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)ethanone (CAS 332376-19-9)
- Semaglutide impurity 29 (CAS 1188328-22-4)
Why CATO?
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