Dichloro[(S)-(-)-2,2',6,6'-tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine][(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II) CAS 821793-36-6
| CAS No. | 821793-36-6 |
| Molecular Formula | C52H50Cl2N4O4P2Ru |
| Molecular Weight | 1028.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dichloro[(S)-(-)-2,2',6,6'-tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine][(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II).
Dichloro[(S)-(-)-2,2',6,6'-tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine][(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II) (CAS 821793-36-6), molecular formula C52H50Cl2N4O4P2Ru and molecular weight 1028.90 g/mol, is a CATO reference standard with documented purity and traceability.
Dichloro[(S)-(-)-2,2',6,6'-tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine][(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II) (C52H50Cl2N4O4P2Ru) contains a nitrogen-containing heterocyclic scaffold, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C52H50Cl2N4O4P2Ru |
| Molecular Weight | 1028.90 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 29.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dichloro Standards
- Dichloro[(R)-(+)-2,2',6,6'-tetramethoxy-4,4'-bis(diphenylphosphino)-3,3'-bipyridine][(1R,2R)-(+)-1,2-diphenylethylenediamine]ruthenium(II) (CAS 478308-91-7)
- Dichloro[(R)-bis(diphenylphosphino)-1,1-binaphthyl][2-(diphenylphosphino)ethylamine]ruthenium(II) (CAS 1097731-98-0)
- Dichloro(3,4,5,6-tetrapropyl-2H-pyran-2-ylidene)bis(triphenylphosphine)platinum (CAS 105430-62-4)
- Dichloro[(S)-(−)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl][(1R,2R)-(+)-1,2-diphenylethylenediamine] ruthenium(II) (CAS 329735-87-7)
- Dichloro[(R)-(-)-4,12-bis(di(3,5-xylyl)phosphino)-[2.2]-paracyclophane][(1S,2S)-(-)-1,2-diphenylethylenediamine]ruthenium(II) (CAS 325150-57-0)
- Dichloro[(S)-(+)-4,12-bis(di(3,5-xylyl)phosphino)-[2.2]-paracyclophane][(1R,2R)-(+)-1,2-diphenylethylenediamine]ruthenium(II) (CAS 364795-64-2)
- Dichloro[(±)−BINAP]digold(I) (CAS 685138-48-1)
- Dichloro[2-(diphenylphosphino-κP)-1-methyl-1H-imidazole-κN3]bis(triphenylphosphine)ruthenium (CAS 804500-06-9)
Recommended Standards
- Ruthenium, [(3S)-4,4'-bis(diphenylphosphino-κP)-2,2',6,6'-tetramethoxy-3,3'-bipyridine]dichloro[(1R,2R)-1,2-diphenyl-1,2-ethanediamine-κN1,κN2] (CAS 916826-86-3)
- Everolimus Impurity 26 (CAS CATO-C4X-112226)
- Ixazomib Impurity 29 (CAS 1201903-03-8)
- Everolimus Impurity 21 (CAS 143030-02-8)
- 4-Methoxy-7-methyl-1H-indole (CAS 203003-67-2)
- 2-Piperazinecarboxylic acid, 4-(triphenylmethyl)-, methyl ester (CAS 1709876-82-3)
- 7-(4-Chlorophenoxy)-3-phenyl-2,3-dihydro-1H-inden-1-ol (CAS 337921-73-0)
- 7a-(Ethoxymethyl)dihydro-1H-[1,3]oxazolo[3,4-c][1,3]oxazole (CAS 749226-79-7)
- 4-Bromo-2-fluorobenzoyl Chloride (CAS 151982-51-3)
- 1-(4,5,6,7-Tetrahydro-1H-indol-2-yl)ethanone (CAS 94393-93-8)
- 5-((3R,5S)-3,5-dimethylpiperazin-1-yl)pyridin-2-amine (CAS 2170791-53-2)
- 2-((3-Cyano-6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-2-yl)thio)-N-(3,4-dimethoxyphenyl)acetamide (CAS 444161-07-3)
- N-(1-Butyl-2-oxo-1,2,3,4-tetrahydroquinolin-6-yl)cyclopentanecarboxamide (CAS 951505-78-5)
- Liraglutide(13-31)TFA Salt (CAS CATO-C4X-19929)
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