Levocetirizine Hydrochloride - API Standards CAS 823178-28-5
| CAS No. | 823178-28-5 |
| Molecular Formula | C21H25ClN2O3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Levocetirizine Hydrochloride - API Standards (CAS 823178-28-5) is a high-purity analytical reference standard with the molecular formula C21H25ClN2O3HCl and a molecular weight of 425.35 g/mol.
Levocetirizine Hydrochloride - API Standards (C21H25ClN2O3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H25ClN2O3 HCl |
| Molecular Weight | 425.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Levocetirizine Standards
- Levocetirizine Impurity 50 (CAS 1074-42-6)
- Levocetirizine Impurity 5 (CAS 109036-15-9)
- Levocetirizine Impurity 43 (CAS 1116338-10-3)
- Levocetirizine Impurity 45 (CAS 1150310-68-1)
- Levocetirizine Dihydrochloride - Impurity H (Hydrochloride Salt) (CAS 1177093-13-8)
- Levocetirizine Impurity 24 (CAS 1232460-29-5)
- Levocetirizine Impurity 80 (CAS 1232460-31-9)
- Levocetirizine Impurity 17 (CAS 126517-38-2)
Recommended Standards
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- 3-(3-cyanophenoxymethyl)furan-2-carboxylic acid (CAS 1094298-96-0)
- 1-(Tert-butoxycarbonyl)-3-(2-fluorophenyl)piperidine-3-carboxylic acid (CAS 2490698-38-7)
- (1S,2R,4S,5R)-2-((S)-Hydroxy(quinolin-4-yl)methyl)-1-(2-oxo-2-((2-phenylpropan-2-yl)amino)ethyl)-5-vinylquinuclidin-1-ium bromide (CAS 2937392-02-2)
- 5-((4-Chlorophenyl)thio)-N-(4-methoxyphenyl)-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 158712-45-9)
- 1-{[(4,4-dimethylcyclohexyl)methyl]sulfanyl}ethan-1-one (CAS 1803609-47-3)
- (R)-3-(4-bromophenyl)pyrrolidine (CAS 1336565-55-9)
- Semaglutide impurity 247 (CAS CATO-C4X-2226247)
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