Sitagliptin EP Impurity A Phosphate (Sitagliptin ((S)-Isomer) Phosphate) CAS 823817-58-9
| CAS No. | 823817-58-9 |
| Molecular Formula | C16H15F6N5O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Sitagliptin EP Impurity A Phosphate (Sitagliptin ((S)-Isomer) Phosphate) under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Sitagliptin EP Impurity A Phosphate (Sitagliptin ((S)-Isomer) Phosphate) (CAS 823817-58-9, C16H15F6N5OH3O4P) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Sitagliptin EP Impurity A Phosphate (Sitagliptin ((S)-Isomer) Phosphate) (C16H15F6N5OH3O4P) contains a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C16H15F6N5O H3O4P |
| Molecular Weight | 505.31 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Sitagliptin Standards
- Sitagliptin Impurity 17 (CAS 1036273-20-7)
- Sitagliptin Impurity 966 (CAS 1151240-88-8)
- Sitagliptin Impurity 14 (CAS 1151240-91-3)
- Sitagliptin Impurity 12 HCl (CAS 1151240-91-3（free base）)
- Sitagliptin Impurity 77 (CAS 1152439-73-0)
- Sitagliptin Impurity 97 (CAS 1169707-29-2)
- Sitagliptin Tablets EP Impurity FP-E HCl (CAS 1204818-19-8)
- Sitagliptin Impurity 15 (CAS 1217809-78-3)
Recommended Standards
- Elagolix Impurity 112 (CAS CATO-C4X-2068112)
- Vonoprazan Fumarate Impurity 81 (CAS CATO-C4X-102081)
- Nitroso Perindopril EP impurity R (CAS CATO-C4X-125255)
- Methyl 3-azabicyclo[3.2.1]octane-1-carboxylate (CAS 1782362-88-2)
- 36600-71-2 Ethyl 2-(4-tert-butylbenzyl)-3-oxobutanoate (CAS 36600-71-2)
- 3-Phenyl-1-pyridin-2-yl-1H-pyrazol-5-ol (CAS 140397-82-6)
- Butyl 2-amino-5-bromobenzoate (CAS 1131587-67-1)
- Methyl 4-((2-methoxyethoxy)methyl)benzoate (CAS 119828-59-0)
- 2-(propan-2-yl)-6’-oxaspiro[azetidine-3,3’-bicyclo[3.1.0]hexane]-4-one (CAS 2031260-36-1)
- Tirzepatide Impurity 61 (CAS CATO-C4X-324061)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com