4-(Trimethylsilyl)-1H-indole CAS 82645-11-2

Purity 97%+In StockPharmaceutical Standards
CAS No.82645-11-2
Molecular FormulaC11H15NSi
Molecular Weight189.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

4-(Trimethylsilyl)-1H-indole CAS 82645-11-2 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

4-(Trimethylsilyl)-1H-indole (CAS 82645-11-2) is a high-purity analytical reference standard with the molecular formula C11H15NSi and a molecular weight of 189.33 g/mol.

The molecular framework of 4-(Trimethylsilyl)-1H-indole (C11H15NSi) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

As a certified reference material (CRM), 4-(Trimethylsilyl)-1H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H15NSi
Molecular Weight189.33 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Nitrogen Atoms1

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