Raloxifene hydrochloride CAS 82640-04-8
| CAS No. | 82640-04-8 |
| Molecular Formula | C28H27NO4S |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Raloxifene hydrochloride (CAS 82640-04-8), molecular formula C28H27NO4SHCl and molecular weight 510.05 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Raloxifene hydrochloride (C28H27NO4SHCl) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Raloxifene hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H27NO4S HCl |
| Molecular Weight | 510.05 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Raloxifene Standards
- Raloxifene Impurity 23 (CAS 102005-47-0)
- Raloxifene Impurity 19 (CAS 1100049-65-7)
- Raloxifene Impurity 18 (CAS 1100049-66-8)
- Raloxifene EP Impurity A (CAS 1159977-58-8)
- Raloxifene-d4 Bismethyl Ether (CAS 1185006-58-9)
- Raloxifene D4 (CAS 1185076-44-1)
- Raloxifene-d4 HCl (CAS 1188263-47-9)
- Raloxifene Impurity 4 (CAS 1191901-07-1)
Recommended Standards
- 6-Chloro-7-nitroquinoline (CAS 226073-82-1)
- 4-(2-Methoxyphenyl)pyrimidine-2-thiol (CAS 1065101-28-1)
- (2-methoxyphenyl)(5-methyl-1,2,4-oxadiazol-3-yl)methanamine hydrochloride (CAS 1306606-21-2)
- 2-Bromo-5-nitroisonicotinamide (CAS 1804407-80-4)
- 1-(Thieno[2,3-b]pyridin-5-yl)ethanamine (CAS 1378814-14-2)
- 2-(4-Fluorophenyl)-5-(piperidin-4-yl)-1,3,4-oxadiazole hydrobromide (CAS 401568-20-5)
- 5-[1-(4-Chlorobenzenesulfonyl)pyrrolidin-2-yl]-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole (CAS 478045-81-7)
- 4-(Chloromethyl)picolinonitrile hydrochloride (CAS 193001-89-7)
- 2-(4-Isopropoxyphenyl)-8-methylquinoline-4-carboxylic acid (CAS 438226-06-3)
- [Glu]17-Semaglutide (CAS CATO-CPTD788604)
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