Ethyl 2,6-dichloro-5-fluoronicotinate CAS 82671-03-2
| CAS No. | 82671-03-2 |
| Molecular Formula | C8H6Cl2FNO2 |
| Molecular Weight | 238.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Ethyl 2,6-dichloro-5-fluoronicotinate (CAS 82671-03-2) is a high-purity analytical reference standard with the molecular formula C8H6Cl2FNO2 and a molecular weight of 238.04 g/mol.
The molecular framework of Ethyl 2,6-dichloro-5-fluoronicotinate (C8H6Cl2FNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Ethyl 2,6-dichloro-5-fluoronicotinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2FNO2 |
| Molecular Weight | 238.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- 2-(2,4-Dichloro-5-fluorophenoxy)acetamide (CAS 1211512-26-3)
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- 2,3-Dichloro-6-(difluoromethoxy)benzonitrile (CAS 1803713-14-5)
- 3,6-Dichloro-2-(difluoromethoxy)benzonitrile (CAS 1803713-18-9)
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- 2,3-Dichloro-4-(difluoromethoxy)benzonitrile (CAS 1803788-55-7)
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- 6-bromo-4-hydroxypyrazolo[1,5-a]pyridine-3-carbonitrile (CAS 2068065-16-5)
- 2-Chloro-3,4-bis((4-methoxybenzyl)oxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide (CAS 1225208-44-5)
- (4-(Difluoromethoxy)benzo[d]oxazol-2-yl)methanol (CAS 1806342-74-4)
- 4-[(E)-2-(2,4-Dichlorophenyl)ethenyl]-6-phenoxy-2H,3H-thieno[3,2-c]quinoline (CAS 866133-77-9)
- Brivaracetam Impurity 58 (CAS CATO-C4X-200758)
- Ethyl 2-(4,4-Difluorocyclohexyl)acetate (CAS 915213-54-6)
- 2-Amino-4-(trifluoromethyl)pyridine-3-acetonitrile (CAS 1228898-39-2)
- 4-(Cyclohexylmethyl)-3-iodophenol (CAS 1243284-21-0)
- 8-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-8-azabicyclo[3.2.1]octan-3-ol (CAS 1495992-24-9)
- (4-(Benzylamino)-6-chloropyrimidin-5-yl)methanol (CAS 1135283-48-5)
- Semaglutide impurity 244(Fmoc-His(Fmoc)-Aib-OH) (CAS CATO-C4X-2226244)
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