2-Bromo-4-chloro-6-nitroaniline CAS 827-25-8
| CAS No. | 827-25-8 |
| Molecular Formula | C6H4BrClN2O2 |
| Molecular Weight | 251.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Bromo-4-chloro-6-nitroaniline (CAS 827-25-8), molecular formula C6H4BrClN2O2 and molecular weight 251.47 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H4BrClN2O2, 2-Bromo-4-chloro-6-nitroaniline contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 251.47 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4BrClN2O2 |
| Molecular Weight | 251.47 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-3-chloro-2-nitroaniline (CAS 1000573-99-8)
- Methyl 6-bromo-5-chloropyrazine-2-carboxylate (CAS 1017603-87-0)
- 3-Bromo-2-chloro-4-methyl-5-nitropyridine (CAS 1049706-73-1)
- 2-Bromo-5-chloro-4-methyl-3-nitropyridine (CAS 1086838-26-7)
- methyl 3-bromo-5-chloro-pyrazine-2-carboxylate (CAS 1211592-50-5)
- 2-Bromo-6-chloro-3-methyl-5-nitropyridine (CAS 1225348-48-0)
- Methyl 6-Bromo-3-chloropyrazine-2-carboxylate (CAS 1256921-67-1)
- 2-Bromo-5-(chloromethyl)-3-nitropyridine (CAS 1379359-69-9)
Recommended Standards
- 2-Bromo-4-chloro-5-nitroaniline (CAS 872266-26-7)
- 3-Bromo-2-chloro-5-nitro-6-picoline (CAS 856834-95-2)
- 2-Amino-6-bromo-5-chloronicotinic acid (CAS 2230875-16-6)
- 3-Bromo-2-chloro-6-nitroaniline (CAS 2091859-73-1)
- 3-(3-Methyl-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonic acid (CAS 85554-80-9)
- 3-Cyclopropoxy-5-iodo-N,N-dimethylpicolinamide (CAS 1243403-56-6)
- (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(3-methylpiperazin-1-yl)methanone hydrochloride (CAS 1353980-53-6)
- 2,2,5,5-Tetramethyltetrahydrofuran-3-amine hydrochloride (CAS 857789-97-0)
- (3,5-Difluorophenyl)(oxazol-2-yl)methanone (CAS 898760-50-4)
- 2-[(3-Amino-2-pyridinyl)(ethyl)amino]-1-ethanol (CAS 1082137-91-4)
- 5,6,7,8-Tetrahydro-4H-cyclohepta[d][1,3]thiazol-2-amine (CAS 14292-44-5)
- 2,3-Dichloro-6-bromobenzoic acid (CAS 887584-64-7)
- Dimethyl(N,N,N',N'-tetramethylethylenediamine)nickel (CAS 122905-76-4)
- Prolactin-Releasing Peptide (12-31) (human) (CAS 235433-36-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com