2-(4,4-Bis(4-fluorophenyl)butyl)-1,2,3,4-tetrahydroisoquinoline CAS 827309-91-1
| CAS No. | 827309-91-1 |
| Molecular Formula | C25H25F2N |
| Molecular Weight | 377.47 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 2-(4,4-Bis(4-fluorophenyl)butyl)-1,2,3,4-tetrahydroisoquinoline is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 377.47 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(4,4-Bis(4-fluorophenyl)butyl)-1,2,3,4-tetrahydroisoquinoline (CAS 827309-91-1), molecular formula C25H25F2N and molecular weight 377.47 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H25F2N |
| Molecular Weight | 377.47 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 1-(Tert-butyl) 4-ethyl 4-(4-methoxybenzyl)piperidine-1,4-dicarboxylate (CAS 932710-58-2)
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- Salutaridinol 7-O-Acetate (CAS 156756-20-6)
- Paroxetine Impurity 44 (CAS 317323-77-6)
- 4-(3-(Trifluoromethyl)phenyl)-4,5,6,7-tetrahydro-3H-imidazo[4,5-c]pyridine (CAS 477871-72-0)
- Trioctylphosphine selenide (CAS 20612-73-1)
- Tert-butyl 4-(6-chloro-2-oxoindolin-3-yl)piperidine-1-carboxylate (CAS 917917-50-1)
- 84030-21-7 N,N,N-Tributyl-1-butanaminium Sulfide Tetrabutylammonium Mercaptide Tetrabutylammonium hydrogen sulfide (CAS 84030-21-7)
- 4-(2-(2-(2-Methoxyethoxy)ethoxy)ethyl)piperidine (CAS 1220178-01-7)
- Ethyl 1-benzyl-4-methylpyrrolidine-3-carboxylate (CAS 351370-91-7)
- N,3-dimethyl-N-(piperidin-3-yl)thiophene-2-carboxamide hydrochloride (CAS 1353981-59-5)
- (S)-4-(4-Bromo-2-formylphenyl)-1-(tert-butoxycarbonyl)piperazine-2-carboxylic acid (CAS 2105411-07-0)
- Sertraline Impurity 28 (CAS CATO-C4X-134428)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
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