6-Fluoro-3,5-dimethoxy-1,2,4-triazine CAS 82736-99-0
| CAS No. | 82736-99-0 |
| Molecular Formula | C5H6FN3O2 |
| Molecular Weight | 159.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Fluoro-3,5-dimethoxy-1,2,4-triazine (CAS 82736-99-0) is a high-purity analytical reference standard with the molecular formula C5H6FN3O2 and a molecular weight of 159.12 g/mol.
The molecular framework of 6-Fluoro-3,5-dimethoxy-1,2,4-triazine (C5H6FN3O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 6-Fluoro-3,5-dimethoxy-1,2,4-triazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H6FN3O2 |
| Molecular Weight | 159.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Fluoro Standards
- 5-Fluoro-1,3-dimethyl-4-nitro-1h-pyrazole (CAS 1392274-44-0)
- 1-(2-Fluoro-ethyl)-3-nitro-1h-pyrazole (CAS 1429419-08-8)
- 3-Fluoro-5,6-dimethoxy-1,2,4-triazine (CAS 82737-01-7)
- 5-Fluoro-4-(methoxyamino)pyrimidin-2(1H)-one (CAS 85931-95-9)
- 2-Fluoro-1-(5-fluoropyridin-3-yl)ethan-1-ol (CAS 2228890-21-7)
- 1-Acetyl-5-fluoro-3-methylpyrrolidin-2-one (CAS 246181-65-7)
- 5-Fluoro-3-azabicyclo[3.1.1]Heptane-1-carboxylic acid (CAS 2402829-93-8)
- 6-fluoro-3H-pyrrolo[2,1-f][1,2,4]triazin-4-one (CAS 2306262-72-4)
Recommended Standards
- 6-Amino-5-fluoro-1-methylpyrimidine-2,4(1H,3H)-dione (CAS 250658-21-0)
- Ethyl 5-fluoroisoxazole-4-carboxylate (CAS 25786-81-6)
- 5-Nitro-1,3,4-thiadiazole-2-carbaldehyde (CAS 29422-56-8)
- rel-(2R,3R)-3-(Ethoxycarbonyl)oxirane-2-carboxylic acid (CAS 63734-73-6)
- 1,1-Dibutyl-2-((2,6-dimethylphenyl)carbamoyl)piperidin-1-ium iodide (CAS 852669-91-1)
- 4-Bromo-5-chloropyridin-3-amine (CAS 1802434-30-5)
- Methyl 6-(diethylamino)-5-methylnicotinate (CAS 37444-48-7)
- rac-trans-4-Hydroxy Tolvaptan (CAS CATO-C4X-195584)
- Methyl (S)-4-Amino-3-[(2-oxetanylmethyl)amino]benzoate (CAS 2230200-74-3)
- (10-(4-(Naphthalen-2-yl)phenyl)anthracen-9-yl)boronic acid (CAS 853945-48-9)
- 3-Hydroxy-2,3-Dihydro-1h-indol-2-one (CAS 61-71-2)
- 1-Bromo-2-cyclopentylbenzene (CAS 59734-90-6)
- 2-Methyl-4-(piperazin-1-yl)benzaldehyde (CAS 1409787-47-8)
- Semaglutide Impurity 82 (CAS CATO-C4X-222682)
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