N-(4-Chloro-5-(pyrrolidin-1-yl)thiazol-2-yl)nicotinamide CAS 828921-03-5
| CAS No. | 828921-03-5 |
| Molecular Formula | C13H13ClN4OS |
| Molecular Weight | 308.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-(4-Chloro-5-(pyrrolidin-1-yl)thiazol-2-yl)nicotinamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-(4-Chloro-5-(pyrrolidin-1-yl)thiazol-2-yl)nicotinamide (CAS 828921-03-5) is a high-purity analytical reference standard with the molecular formula C13H13ClN4OS and a molecular weight of 308.79 g/mol.
The molecular framework of N-(4-Chloro-5-(pyrrolidin-1-yl)thiazol-2-yl)nicotinamide (C13H13ClN4OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H13ClN4OS |
| Molecular Weight | 308.79 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(4-Chloro-5-(pyrrolidin-1-yl)thiazol-2-yl)isonicotinamide (CAS 828921-04-6)
- 2-chloro-N-[1-(3-phenylpropanoyl)piperidin-4-yl]acetamide (CAS 1311315-50-0)
- 5-Chloro-n-(2-cyanoethyl)-n-(2-methoxyethyl)thiophene-2-sulfonamide (CAS 1311775-96-8)
- 1-(2-Chloro-4-fluorophenyl)-3-(4-(methylthio)phenyl)propan-1-one (CAS 898781-61-8)
- 1-(3-Chloro-5-fluorophenyl)-3-(4-(methylthio)phenyl)propan-1-one (CAS 898781-63-0)
- 1-(4-Chloro-2-fluorophenyl)-3-(4-(methylthio)phenyl)propan-1-one (CAS 898781-65-2)
- 1-(4-Chloro-3-fluorophenyl)-3-(4-(methylthio)phenyl)propan-1-one (CAS 898781-42-5)
- 2-Benzyl-10-chloro-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine (CAS 219537-08-3)
Recommended Standards
- 2-(4-Chlorophenyl)-1,1-diphenylethanol (CAS 109936-21-2)
- 2,4,6-Triphenyl-1,3,5,2,4,6-triazatriborinane (CAS 976-28-3)
- Cis-Tert-Butyl8-Chloro-3,4,4A,5-Tetrahydro-1H-Pyrido[4,3-B]Indole-2(9Bh)-Carboxylate (CAS 1250994-53-6)
- Clobazam-d8 (CAS 1263274-30-1)
- (3AR,5S,6R,6aR)-5-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-6-methoxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole (CAS 29587-01-7)
- (S)-(2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazol-2-yl)methanol (CAS 1217756-56-3)
- Methyl 3-hydroxy-5-methylpicolinate (CAS 1806316-67-5)
- 2-Methyl-2-(piperidin-4-yl)propan-1-ol (CAS 99203-25-5)
- Tert-butyl (R)-6-(1-hydroxyethyl)-3,4-dihydro-1,5-naphthyridine-1(2H)-carboxylate (CAS 2387561-37-5)
- 2-Oxo-2-(phenylamino)ethyl quinoline-2-carboxylate (CAS 749894-98-2)
- Methyl 4-(4-chloro-3-fluorophenyl)-4-oxobutanoate (CAS 1247500-98-6)
- (1S,4s)-4-((7-morpholinoquinoxalin-5-yl)oxy)cyclohexan-1-amine (CAS 1628908-34-8)
- 3,4-Dihydro-4,4-dimethyl-2H-pyran-2-one (CAS 76897-39-7)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com