2-Hydroxy-3-methoxybenzoyl chloride CAS 82944-14-7
| CAS No. | 82944-14-7 |
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-Hydroxy-3-methoxybenzoyl chloride (CAS 82944-14-7) is a high-purity analytical reference standard with the molecular formula C8H7ClO3 and a molecular weight of 186.59 g/mol.
2-Hydroxy-3-methoxybenzoyl chloride (C8H7ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H7ClO3 |
| Molecular Weight | 186.59 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | Cl-containing |
Related Hydroxy Standards
- 2-Hydroxy-4-methoxybenzoyl chloride (CAS 15198-08-0)
- 2-Hydroxy-5-methoxybenzoyl chloride (CAS 15198-09-1)
- 3-Hydroxy-4-methoxybenzoyl Chloride (CAS 289896-68-0)
- Ethyl 4-hydroxy-1-methylcyclohexanecarboxylate (CAS 104036-19-3)
- 10-Hydroxy-(E)-8-decenoic Acid (CAS 106541-97-3)
- N'-Hydroxy-3-(4-methylpiperazin-1-yl)propanimidamide (CAS 108372-23-2)
- Ethyl 4-Hydroxy-4-methylcyclohexanecarboxylate (CAS 1170735-91-7)
- 1-Hydroxy-4-propylcyclohexane-1-carboxylic acid (CAS 1250909-01-3)
Recommended Standards
- 2-Chloro-6-methoxybenzoic acid (CAS 3260-89-7)
- 2-Methoxyphenyl carbonochloridate (CAS 2293-75-6)
- 2-Chloro-5-methoxybenzoic Acid (CAS 6280-89-3)
- 3-Chloro-2-hydroxy-4-methoxybenzaldehyde (CAS 72482-15-6)
- 3-[(2,6-Dichlorophenyl)methyl]-2-methyl-1-[(4-methylphenyl)methyl]-1,4-dihydropyridin-4-one (CAS 339104-32-4)
- n-(4-Phenoxyphenyl)prop-2-enamide (CAS 134046-78-9)
- 2-Ethoxy-5-methylpyridin-3-ol (CAS 1881328-39-7)
- 3-(tert-Butyl)-2-hydroxy-5-(4-pyridyl)benzaldehyde (CAS 342037-22-3)
- 3-(Ethylamino)pyrazine-2-carboxamide (CAS 887577-59-5)
- 6-bromo-3,8-dimethyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1500937-08-5)
- 3-tert-Butyl 2-methyl 4,5-dihydro-1H-benzo[d]azepine-2,3(2H)-dicarboxylate (CAS 188990-13-8)
- 6-Methyl-4-(pyrrolidin-1-yl)-2H-pyran-2-one (CAS 80556-43-0)
- 3-Amino-N-cyclopentyl-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 625370-23-2)
- D-Leu26-Tirzepatide (CAS CATO-CPTD788908)
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