3-Bromo-4-(difluoromethoxy)aniline CAS 83189-98-4
| CAS No. | 83189-98-4 |
| Molecular Formula | C7H6BrF2NO |
| Molecular Weight | 238.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Bromo-4-(difluoromethoxy)aniline (CAS 83189-98-4) is a high-purity analytical reference standard with the molecular formula C7H6BrF2NO and a molecular weight of 238.03 g/mol.
Based on its molecular formula C7H6BrF2NO, 3-Bromo-4-(difluoromethoxy)aniline contains an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 238.03 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H6BrF2NO |
| Molecular Weight | 238.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 2-Bromo-4-(difluoromethoxy)aniline (CAS 1000574-79-7)
- 4-Bromo-2-(difluoromethoxy)aniline (CAS 1000575-14-3)
- 5-Bromo-2-(difluoromethoxy)-4-methylpyridine (CAS 1079352-13-8)
- 5-bromo-3-(difluoromethoxy)-2-methylpyridine (CAS 1211536-99-0)
- 4-Bromo-2-(difluoromethoxy)-6-methylpyridine (CAS 1227184-58-8)
- 3-Bromo-5-(2,2-difluoroethoxy)pyridine (CAS 1241752-27-1)
- 5-Bromo-3-(difluoromethyl)-2-methoxypyridine (CAS 1254123-51-7)
- 5-Bromo-2-(difluoromethoxy)aniline (CAS 1258650-63-3)
Recommended Standards
- 3-Bromo-2-(difluoromethoxy)aniline (CAS 259243-50-0)
- 3-Iodo-4-methoxy-1-methyl-1H-pyrazole (CAS 2203333-07-5)
- 3-Bromo-1-cyclopropyl-5-(difluoromethyl)-1H-1,2,4-triazole (CAS 2755894-04-1)
- 4-Bromo-3-(difluoromethoxy)aniline (CAS 87967-37-1)
- 3-Hydroxy-5-(trifluoromethyl)picolinamide (CAS 1806531-31-6)
- 4-Methoxy-3-oxobutanenitrile (CAS 739366-02-0)
- 2-Ethyl-2-methylpiperidine (CAS 585544-35-0)
- 2-Methyl-3-(trifluoromethyl)phenol (CAS 934180-47-9)
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- N-(2-(Dimethylamino)-6-methoxypyrimidin-4-yl)acetamide (CAS 3550-73-0)
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