1-(Difluoromethoxy)-2-fluoro-4-nitrobenzene CAS 83189-99-5
| CAS No. | 83189-99-5 |
| Molecular Formula | C7H4F3NO3 |
| Molecular Weight | 207.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 1-(Difluoromethoxy)-2-fluoro-4-nitrobenzene (CAS 83189-99-5), a certified reference material (molecular formula C7H4F3NO3, MW 207.11 g/mol) for analytical method development and quality control.
Structurally, 1-(Difluoromethoxy)-2-fluoro-4-nitrobenzene (C7H4F3NO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 207.11 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 1-(Difluoromethoxy)-2-fluoro-4-nitrobenzene meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H4F3NO3 |
| Molecular Weight | 207.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoromethoxy Standards
- 2-(Difluoromethoxy)-1-fluoro-3-nitrobenzene (CAS 1214326-22-3)
- 1-(Difluoromethoxy)-2-fluoro-3-nitrobenzene (CAS 1214326-24-5)
- 2-(Difluoromethoxy)-4-fluoro-1-nitrobenzene (CAS 1214329-62-0)
- 3-(Difluoromethoxy)-5-fluoronitrobenzene (CAS 1214332-99-6)
- 4-(Difluoromethoxy)-2-fluoro-1-nitrobenzene (CAS 1214336-83-0)
- 1-(Difluoromethoxy)-3-fluoro-2-nitrobenzene (CAS 1214336-89-6)
- 1-(Difluoromethoxy)-4-fluoro-2-nitrobenzene (CAS 1214349-53-7)
- 6-(Difluoromethoxy)-3-fluoropyridine-2-carboxylic acid (CAS 1214386-58-9)
Recommended Standards
- 1-(Bromomethyl)-1-methoxycyclohexane (CAS 22690-23-9)
- 1-Bromo-2-ethoxycyclohexane (CAS 861337-57-7)
- 1-(2-Bromoethyl)cyclohexan-1-ol (CAS 40894-06-2)
- 1-bromooctan-2-one (CAS 26818-08-6)
- 4-Amino-5-(2-methylfuran-3-yl)-4H-1,2,4-triazole-3-thiol (CAS 560998-03-0)
- 4-(2-Methoxyethyl)phenyl 3-piperidinyl ether (CAS 946681-36-3)
- 1-(2-Chloro-5-fluorophenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 1291837-07-4)
- (5-methyl-1-benzofuran-2-yl)methanamine (CAS 165737-47-3)
- N-(3-bromopyridin-2-yl)-2-cyanoacetamide (CAS 1507694-97-4)
- 9,10-Dihydro-1-benzo[a]pyrene-7(8H)-one Oxime (CAS 88909-82-4)
- 3-Fluoro-4-nitrobenzenesulfonyl Chloride (CAS 86156-93-6)
- 6-Chloroquinolin-5-ol (CAS 1236162-17-6)
- 3,5-Dimethyl-2-propionylcyclohexan-1-one (CAS 1071674-23-1)
- Hexapeptide-11 (CAS 161258-30-6)
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