3-Amino-6-(difluoromethyl)-4-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide CAS 832737-16-3

Purity 97%+In StockPharmaceutical Standards
CAS No.832737-16-3
Molecular FormulaC16H13F2N3OS
Molecular Weight333.36 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-Amino-6-(difluoromethyl)-4-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide CAS 832737-16-3 chemical structure

Description

CATO supplies 3-Amino-6-(difluoromethyl)-4-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (CAS 832737-16-3), a certified reference material (molecular formula C16H13F2N3OS, MW 333.36 g/mol) for analytical method development and quality control.

The molecular framework of 3-Amino-6-(difluoromethyl)-4-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide (C16H13F2N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 3-Amino-6-(difluoromethyl)-4-(p-tolyl)thieno[2,3-b]pyridine-2-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC16H13F2N3OS
Molecular Weight333.36 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1986
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms1

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