(2,6-Difluoro-3-((2-fluorobenzyl)oxy)phenyl)boronic acid CAS 836615-83-9
| CAS No. | 836615-83-9 |
| Molecular Formula | C13H10BF3O3 |
| Molecular Weight | 282.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 282.02 g/mol gives (2,6-Difluoro-3-((2-fluorobenzyl)oxy)phenyl)boronic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(2,6-Difluoro-3-((2-fluorobenzyl)oxy)phenyl)boronic acid (CAS 836615-83-9) is a high-purity analytical reference standard with the molecular formula C13H10BF3O3 and a molecular weight of 282.02 g/mol.
(2,6-Difluoro-3-((2-fluorobenzyl)oxy)phenyl)boronic acid (C13H10BF3O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H10BF3O3 |
| Molecular Weight | 282.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | F-containing |
Related Difluoro Standards
- 2,2-Difluoro-2-iodo-1-phenylethanone (CAS 150542-06-6)
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- 1-(2,4-Difluoro-3-iodophenyl)ethanone (CAS 2383443-66-9)
- 1-(2,6-Difluoro-3-iodophenyl)ethanone (CAS 746630-32-0)
- (5,6-Difluoro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl)boronic acid (CAS 2759141-28-9)
- 2,2-Difluoro-2-(1,1,2,2-tetrafluoro-2-(trifluoromethoxy)ethoxy)ethan-1-ol (CAS 330562-43-1)
- 2,3-Difluoro-1-iodo-4-propylbenzene (CAS 928208-52-0)
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Recommended Standards
- ((4S,5R)-2-(Ethoxycarbonyl)-4,5-dimethyl-5-(trifluoromethyl)-4,5-dihydrofuran-3-yl)boronic acid (CAS 2649471-18-9)
- (4-[3-(Trifluoromethyl)phenoxy]phenyl)boranediol (CAS 958457-42-6)
- 4-Amino-5-bromo-6-(trifluoromethoxy)nicotinonitrile (CAS 1803448-02-3)
- {4-[4-(Trifluoromethoxy)phenyl]phenyl}boronic acid (CAS 501944-50-9)
- Pilocarpine HCl (CAS 54-71-7)
- 2,3-Dihydro-1H-benz[f]inden-1-one (CAS 109341-49-3)
- 5-methoxy-1,3,4-thiadiazole-2-thiol (CAS 37158-90-0)
- Ethyl 2-imino-2-(2-(2-phenylacetyl)hydrazinyl)acetate (CAS 107469-64-7)
- 3-(2,2-Dimethylpropyl)-6-methyl-[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid (CAS 954577-39-0)
- (S)-3-(4-Fluorophenoxy)pyrrolidine (CAS 1187927-92-9)
- 3-Amino-2-(2-chloro-4-fluorophenyl)propan-1-ol (CAS 1515221-49-4)
- Hederacolchiside A1 (CAS 106577-39-3)
- 4-Hydroxy-1-(4-methylphenyl)-6-oxo-1,6-dihydropyridazine-3-carbohydrazide (CAS 1481223-59-9)
- Delta-Sleep Inducing Peptide (CAS 62568-57-4)
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