Zolpidem EP Impurity D CAS 836627-56-6
| CAS No. | 836627-56-6 |
| Molecular Formula | C13H16BrNO2 |
| Molecular Weight | 298.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 298.18 g/mol gives Zolpidem EP Impurity D distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Zolpidem EP Impurity D (CAS 836627-56-6), a pharmacopoeial impurity reference standard (molecular formula C13H16BrNO2, MW 298.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C13H16BrNO2, Zolpidem EP Impurity D contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 298.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H16BrNO2 |
| Molecular Weight | 298.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1986 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Zolpidem Standards
- Zolpidem Impurity 10 (CAS 258273-50-6)
- 【禁售不询】Zolpidem (CAS 82626-48-0)
- Zolpidem USP RC A（Zolpidem EP Impurity A） (CAS 1346600-85-8)
- Zolpidem Impurity 9 (CAS CATO-C4X-14869)
- Zolpidem Impurity 15 (CAS 258273-49-3)
- Zolpidem D6 (CAS 959605-90-4)
- Zolpidem Acid Impurity 2 (CAS 189005-44-5)
- Zolpidem Amide (CAS 365213-58-7)
Recommended Standards
- Aripiprazole Impurity 64 (CAS 63136-84-5)
- Aripiprazole N-Bromobutyl Impurity (CAS 1424857-68-0)
- Aripiprazole Impurity 61 (CAS 63309-35-3)
- N-Boc-imidazole-2-boronic acid (CAS 1198605-51-4)
- Brexpiprazole Impurity 90 (CAS CATO-C4X-113190)
- Cariprazine Impurity 40 (CAS CATO-C4X-240840)
- Kitasamycin impurity 1 (CAS CATO-C4X-33801)
- 854860-48-3 2,5-Dimethyl-4-nitrobenzene-1-sulfonyl chloride MFCD19200434 (CAS 854860-48-3)
- 3-Bromo-4-ethyl-4H-1,2,4-triazole (CAS 64907-56-8)
- Ethyl 4-(3,4-dimethoxyphenyl)-2-oxo-2,3-dihydrothiazole-5-carboxylate (CAS 886497-86-5)
- N-Cyclohexylpiperazine-1-carboxamide (CAS 923177-04-2)
- 4-Bromo-3-(4H-1,2,4-triazol-4-yl)-1H-pyrazole-5-carboxylic acid (CAS 1239470-64-4)
- N-(2,5-Dichlorobenzyl)-1-(pyrrolidin-2-yl)methanamine hydrochloride (CAS 1261232-22-7)
- Semaglutide impurity 260 (CAS CATO-C4X-2226260)
Why CATO?
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