Aripiprazole Impurity 61 CAS 63309-35-3
| CAS No. | 63309-35-3 |
| Molecular Formula | C13H16BrNO2 |
| Molecular Weight | 298.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Aripiprazole Impurity 61 (CAS 63309-35-3, C13H16BrNO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Aripiprazole Impurity 61 (C13H16BrNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Aripiprazole Impurity 61 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16BrNO2 |
| Molecular Weight | 298.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Aripiprazole Standards
- Aripiprazole Impurity 3 (CAS 129722-34-5)
- Aripiprazole Impurity 64 (CAS 63136-84-5)
- Aripiprazole N-Bromobutyl Impurity (CAS 1424857-68-0)
- Aripiprazole Impurity N9 (CAS 870765-38-1)
- Aripiprazole Impurity 71 (CAS CATO-C4X-100871)
- Aripiprazole Impurity 21 (CAS 2250243-33-3)
- Aripiprazole Impurity 48 (CAS 1424857-93-1)
- Aripiprazole-Impurity 10 (CAS 82657-32-7)
Recommended Standards
- tert-Butyl 5-Bromoisoindoline-2-carboxylate (CAS 201940-08-1)
- Zolpidem EP Impurity D (CAS 836627-56-6)
- Tert-butyl (2S,3S)-3-(3-bromophenyl)aziridine-2-carboxylate (CAS 1980008-31-8)
- Tert-butyl (2S,3R)-3-(3-bromophenyl)aziridine-2-carboxylate (CAS 1980008-30-7)
- Oseltamivir impurity 235 (CAS CATO-C4X-1720235)
- Upadacitinib Impurity 157 (CAS CATO-C4X-2405157)
- Avibactam Impurity 2 (CAS 2606850-80-8(free base))
- Valbenazine Impurity 4 (CAS 1025504-59-9)
- 1-(4-Fluorophenyl)but-3-enylamine hcl (CAS 1159825-73-6)
- 2,4,6-Tribromophenyl 2-(3-methoxyphenoxy)acetate (CAS 330677-24-2)
- 3H-Pyrrolo[3,2-b]pyridine (CAS 272-48-0)
- 6-Nitroquinoline-2-carboxylic acid (CAS 30836-96-5)
- 1-(Benzo[d][1,3]dioxol-5-yl)-N-phenylmethanimine (CAS 853099-64-6)
- D-[Thr]7-Liraglutide (CAS CATO-C4X-199237)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com