2-(3-(Trifluoromethoxy)phenyl)quinazolin-4(1H)-one CAS 83800-85-5
| CAS No. | 83800-85-5 |
| Molecular Formula | C15H9F3N2O2 |
| Molecular Weight | 306.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2-(3-(Trifluoromethoxy)phenyl)quinazolin-4(1H)-one (CAS 83800-85-5), a certified reference material (molecular formula C15H9F3N2O2, MW 306.24 g/mol) for analytical method development and quality control.
The molecular framework of 2-(3-(Trifluoromethoxy)phenyl)quinazolin-4(1H)-one (C15H9F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H9F3N2O2 |
| Molecular Weight | 306.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1980 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethoxy Standards
- 2-(4-(Trifluoromethoxy)phenyl)phthalazin-1(2H)-one (CAS 161716-16-1)
- 2-(4-(Trifluoromethoxy)phenyl)quinazolin-4(1H)-one (CAS 83800-84-4)
- 3-(2-(Trifluoromethoxy)phenyl)-5,6,7,8-tetrahydro-5,8-methanocinnoline (CAS 918874-62-1)
- 1-[trans-7-[4-(trifluoromethoxy)phenyl]-2-oxaspiro[3.3]heptan-6-yl]ethanone (CAS 2624261-49-8)
- (Z)-3-(4-(trifluoromethoxy)benzylidene)indolin-2-one (CAS 860784-42-5)
- 3-{[4-(trifluoromethoxy)phenyl]methyl}-2,3-dihydro-1H-indol-2-one (CAS 882747-47-9)
- 2-Methyl-5-(4-trifluoromethoxy-phenyl)-furan-3-carbonyl chloride (CAS 1858242-00-8)
- 1-(Trifluoromethoxy)-2-(((trifluoromethyl)sulfonyl)methyl)benzene (CAS 1346521-39-8)
Recommended Standards
- 2-((3-(Trifluoromethyl)phenyl)amino)-4H-benzo[d][1,3]oxazin-4-one (CAS 282529-88-8)
- 1-[2-(Trifluoromethyl)phenyl]imidazo[1,5-a]pyridine-3-carboxylic acid (CAS 2059993-43-8)
- 2-(6-Hydroxynaphthalen-2-yl)-6-(trifluoromethyl)pyrimidin-4(1H)-one (CAS 651723-13-6)
- 1,1-Dimethylethyl N-[2-nitro-4-(trifluoromethyl)phenyl]carbamate (CAS 579474-18-3)
- Gramine-α,α-d2 (CAS 95415-84-2)
- 1-(6-Thiophen-2-yl-pyridin-3-yl)-ethanone (CAS 2088945-78-0)
- N-(cyclopentylmethyl)-2,2-dimethoxyethan-1-amine (CAS 1248097-77-9)
- 3,3-Dimethyl-2-oxobutyl 2-fluorobenzoate (CAS 474945-57-8)
- 1-(2-Methylpiperidin-1-yl)heptan-1-one (CAS 57150-26-2)
- 6-Amino-2-(trifluoromethyl)pyridine-3-methanol (CAS 1227509-97-8)
- 2-((1S,4R)-bicyclo[2.2.1]Heptan-2-yl)acetic acid (CAS 878798-86-8)
- Alverine Impurity 20 Iodide (CAS 879718-23-7（free base）)
- 8-Bromo-5-nitroisoquinoline (CAS 252861-41-9)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
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