Brimonidine EP Impurity D CAS 842138-74-3
| CAS No. | 842138-74-3 |
| Molecular Formula | C9H7BrN4S |
| Molecular Weight | 283.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Brimonidine EP Impurity D (CAS 842138-74-3) is a certified pharmaceutical impurity reference standard with the molecular formula C9H7BrN4S and a molecular weight of 283.15 g/mol.
Brimonidine EP Impurity D (C9H7BrN4S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C9H7BrN4S |
| Molecular Weight | 283.15 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Brimonidine Standards
- Brimonidine Impurity 20 (CAS 1217439-05-8)
- Brimonidine EP Impurity F (CAS 151110-15-5)
- Brimonidine (CAS 59803-98-4)
- Brimonidine Impurity 17 (CAS 134862-75-2)
- Brimonidine-D4 (CAS 1184971-51-4)
- Brimonidine Impurity 13 (CAS 134892-42-5)
- Brimonidine Impurity 42 (CAS CATO-C4X-156642)
- Brimonidine Impurity 22 (CAS 134892-46-9)
Recommended Standards
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- 4-Sulfamoylphenylboronic Acid Pinacol Ester (CAS 214360-51-7)
- Diosmin Impurity N5 (CAS 122087-66-5)
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