(3-Chloro-4-fluorophenyl)hydrazine CAS 84282-78-0
| CAS No. | 84282-78-0 |
| Molecular Formula | C6H6ClFN2 |
| Molecular Weight | 160.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(3-Chloro-4-fluorophenyl)hydrazine (CAS 84282-78-0), molecular formula C6H6ClFN2 and molecular weight 160.58 g/mol, is a CATO reference standard with documented purity and traceability.
(3-Chloro-4-fluorophenyl)hydrazine (C6H6ClFN2) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H6ClFN2 |
| Molecular Weight | 160.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 5-Chloro-3-fluorobenzene-1,2-diamine (CAS 1106717-48-9)
- (2-Chloro-3-fluorophenyl)hydrazine (CAS 1138218-48-0)
- (3-Chloro-2-fluoropyridin-4-yl)methanamine (CAS 1149588-74-8)
- 2-Chloro-5-fluoro-4,6-dimethylpyrimidine (CAS 1192479-36-9)
- (2-Chloro-4-fluorophenyl)hydrazine (CAS 119452-65-2)
- (3-Chloro-5-fluoropyridin-2-yl)methanamine (CAS 1211578-98-1)
- 4-Chloro-5-fluoro-2,6-dimethylpyrimidine (CAS 1240622-52-9)
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Recommended Standards
- (3-Chloro-2-fluorophenyl)hydrazine (CAS 396075-11-9)
- (4-Chloro-2-fluorophenyl)hydrazine (CAS 64548-20-5)
- (2-Chloro-5-fluoropyridin-4-yl)methanamine (CAS 924706-97-8)
- (5-Chloro-2-fluorophenyl)hydrazine (CAS 396074-99-0)
- 3-((4,8-Dimethylquinolin-2-yl)thio)propanoic acid (CAS 370843-69-9)
- 7-Methoxyisoquinolin-4-ol (CAS 98263-37-7)
- 2-Propenoic acid, 2-methyl-, polymer with ethenylbenzene and methyl 2-methyl-2-propenoate (CAS 25035-81-8)
- (2E)-3-(2-Chloro-6-fluorophenyl)-1-(2-methylphenyl)prop-2-en-1-one (CAS 1354941-06-2)
- 53771-22-5 DL-Mevalonic-2-13C lactone Mevalonolactone-2-13C (CAS 53771-22-5)
- 2-methyl-6-(1H-pyrrol-1-ylmethyl)pyridine (CAS 1251105-57-3)
- n-(4,6-Dimethylpyrimidin-2-yl)-4-(4-methoxyphenyl)piperazine-1-carboximidamide (CAS 674363-57-6)
- (E)-3-([1,1'-biphenyl]-4-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde oxime (CAS 372098-45-8)
- (R)-5-ethyl-1-methylpiperazin-2-one (CAS 1217772-16-1)
- Prolactin-Releasing Peptide (1-31) (human) (CAS 215510-22-8)
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