5-Fluoro-3-methyl-1H-indole-2-carbaldehyde CAS 842972-09-2
| CAS No. | 842972-09-2 |
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 177.18 g/mol gives 5-Fluoro-3-methyl-1H-indole-2-carbaldehyde distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Fluoro-3-methyl-1H-indole-2-carbaldehyde (CAS 842972-09-2) is a high-purity analytical reference standard with the molecular formula C10H8FNO and a molecular weight of 177.18 g/mol.
The molecular framework of 5-Fluoro-3-methyl-1H-indole-2-carbaldehyde (C10H8FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8FNO |
| Molecular Weight | 177.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 5-Fluoro-2-methylquinolin-8-ol (CAS 37026-20-3)
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- 5-Fluoro-2-methyl-1H-indole-3-carbaldehyde (CAS 815586-68-6)
- 5-Fluoro-8-methoxyquinoline (CAS 439-88-3)
- (R)-N-(4-(4-(2-(Diethylamino)-2-oxo-1-phenylethyl)piperazin-1-yl)-3-fluorophenyl)-2-(pyridin-3-yl)benzamide (CAS 1094873-17-2)
- 2-(Methoxymethyl)-6-phenyl-5-styrylpyridazin-3(2H)-one (CAS 404936-86-3)
- 2-(5-Amino-3-(pyrazin-2-yl)-1H-pyrazol-1-yl)ethan-1-ol (CAS 1708037-48-2)
- 4-octadecylaniline (CAS 114235-67-5)
- 1-(3-Amino-4-chlorobenzo[b]thiophen-2-yl)ethanone (CAS 52673-88-8)
- 1-Phenyl-3H,4H,9H-pyrido[3,4-b]indole (CAS 10022-79-4)
- 6,8-Difluoro-1-methyl-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid (CAS 1269534-96-4)
- 1-Cyclopropoxy-3-isopropoxy-2-isopropylbenzene (CAS 1243391-72-1)
- 5-Methylpyrrolidin-3-amine (CAS 396133-22-5)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
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