Trimebutine EP Impurity E CAS 84333-59-5
| CAS No. | 84333-59-5 |
| Molecular Formula | C21H27NO5 |
| Molecular Weight | 373.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Trimebutine EP Impurity E (CAS 84333-59-5) is a certified pharmaceutical impurity reference standard with the molecular formula C21H27NO5 and a molecular weight of 373.44 g/mol.
Structurally, Trimebutine EP Impurity E (C21H27NO5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 373.44 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H27NO5 |
| Molecular Weight | 373.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 1 |
Related Trimebutine Standards
- Trimebutine Impurity 18 (CAS 118291-70-6)
- Trimebutine Impurity 15 (CAS CATO-C4X-185815)
- Trimebutine (CAS 39133-31-8)
- Trimebutine EP Impurity D (CAS 92414-09-0)
- Trimebutine-d5 (CAS 1189928-38-8)
- Trimebutine Impurity 27 (CAS 294882-35-2)
- Trimebutine Impurity 16 (CAS CATO-C4X-185816)
- Trimebutine Impurity 10 (CAS CATO-C4X-185810)
Recommended Standards
- Papaverine impurity 21 (CAS CATO-C4X-206721)
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- Pemafibrate Impurity 2 (CAS CATO-C4X-29032)
- Mivacurium chloride Impurity 26 (CAS 73554-57-1)
- Linagliptin Impurity 135 (CAS CATO-C4X-1101135)
- Tivozanib Impurity 5 (CAS CATO-C4X-34005)
- Reserpine Impurity 9 (CAS 1446557-12-5)
- 6-Bromo-4-fluoro-2,3-dihydro-1H-inden-1-ol (CAS 1248125-21-4)
- Quinoline-4-sulfonic acid (CAS 6046-42-0)
- Ethyl 2,2-Difluoro-2-(1-naphthyl)acetate (CAS 73790-00-8)
- 4-Methoxybenzo[d]thiazol-2(3H)-one (CAS 80567-66-4)
- (R)-1-(2-Benzamidoacetyl)pyrrolidine-2-carboxamide (CAS 177433-42-0)
- 2-(4-chlorophenyl)-1,3-thiazole-4-sulfonamide (CAS 1803581-26-1)
- Tirzepatide Impurity 12 (CAS CATO-C4X-324012)
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