2-(1-{[2-chloro-5-(trifluoromethyl)phenyl]amino}ethylidene)-2,3-dihydro-1H-indene-1,3-dione CAS 843636-53-3
| CAS No. | 843636-53-3 |
| Molecular Formula | C18H11ClF3NO2 |
| Molecular Weight | 365.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(1-{[2-chloro-5-(trifluoromethyl)phenyl]amino}ethylidene)-2,3-dihydro-1H-indene-1,3-dione is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(1-{[2-chloro-5-(trifluoromethyl)phenyl]amino}ethylidene)-2,3-dihydro-1H-indene-1,3-dione (CAS 843636-53-3), a certified reference material (molecular formula C18H11ClF3NO2, MW 365.73 g/mol) for analytical method development and quality control.
2-(1-{[2-chloro-5-(trifluoromethyl)phenyl]amino}ethylidene)-2,3-dihydro-1H-indene-1,3-dione (C18H11ClF3NO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(1-{[2-chloro-5-(trifluoromethyl)phenyl]amino}ethylidene)-2,3-dihydro-1H-indene-1,3-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H11ClF3NO2 |
| Molecular Weight | 365.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 5-(2-Chlorophenyl)-N-(2-(trifluoromethyl)phenyl)furan-2-carboxamide (CAS 853314-68-8)
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- 5-(2-Chlorophenyl)-N-(3-(trifluoromethyl)phenyl)furan-2-carboxamide (CAS 618400-57-0)
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- (S)-7-bromochroman-3-amine (CAS 1335527-60-0)
- 81797-53-7 Trimethylsilane(~13~C,~15~N)carbonitrile DTXSID30745972 (CAS 81797-53-7)
- 2-(Benzo[d][1,3]dioxol-5-yl)pyrrolidine (CAS 95849-38-0)
- 2,5,7,10-Tetraoxaundecane (CAS 4431-83-8)
- 2-amino-N-ethylethane-1-sulfonamide hydrochloride (CAS 1305712-73-5)
- 5,5-Dimethyl-1,3-bis(oxiran-2-ylmethyl)imidazolidine-2,4-dione (CAS 15336-81-9)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
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