3-Acetyl-2-hydroxyquinoline-4-carboxylic acid CAS 84443-15-2
| CAS No. | 84443-15-2 |
| Molecular Formula | C12H9NO4 |
| Molecular Weight | 231.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 3-Acetyl-2-hydroxyquinoline-4-carboxylic acid (C12H9NO4) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 3-Acetyl-2-hydroxyquinoline-4-carboxylic acid (CAS 84443-15-2), a certified reference material (molecular formula C12H9NO4, MW 231.20 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Acetyl-2-hydroxyquinoline-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9NO4 |
| Molecular Weight | 231.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1981 |
| Nitrogen Atoms | 1 |
Related Acetyl Standards
- 6-acetyl-4-hydroxyquinoline-2-carboxylic acid (CAS 91493-55-9)
- 6-acetyl-4-hydroxyquinoline-3-carboxylic acid (CAS 873969-88-1)
- 7-Acetyl-4-hydroxyquinoline-3-carboxylic acid (CAS 63463-21-8)
- 8-Ethyl-4-hydroxyquinoline-3-carbohydrazide (CAS 1315373-86-4)
- 6-Ethyl-4-hydroxyquinoline-3-carbohydrazide (CAS 1329807-25-1)
- Propyl 2-hydroxyquinoline-4-carboxylate (CAS 39497-03-5)
- 4-Hydroxyquinoline-3,8-dicarboxylic acid (CAS 402580-02-3)
- 8-Hydroxyquinoline-2-sulfonic acid (CAS 20946-17-2)
Recommended Standards
- 3-(Furan-2-amido)benzoic acid (CAS 293761-91-8)
- 3-Amino-3-(3-(difluoromethoxy)phenyl)propanoic acid (CAS 773123-55-0)
- 3-(4-Nitrophenoxy)phenol (CAS 22483-31-4)
- 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methylbenzoic acid (CAS 777920-31-7)
- Hydrochlorothiazide Impurity 24 (CAS 1025-75-8)
- 2-(Aminomethyl)-5-chloroindole (CAS 21109-27-3)
- 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)-2-methyl-4H-pyran-4-one (CAS 303151-77-1)
- 3,3,3-Trifluoro-2-(pyridin-3-yloxy)propan-1-amine (CAS 886764-52-9)
- 3-(Cyclohexylmethyl)-5-isopropoxyphenol (CAS 1243386-18-6)
- Pyronaridine Impurity 4 (CAS CATO-C4X-29784)
- 5-(3-Fluoro-5-(trifluoromethyl)phenoxy)furan-2-carboxylic acid (CAS 1255147-75-1)
- (E)-2-(4-chlorophenyl)-7-methylimidazo[1,2-a]pyridine-3-carbaldehyde O-(2,4-dichlorobenzyl) oxime (CAS 478257-12-4)
- 1-(2,3,6-Trimethylphenyl)ethan-1-one (CAS 54200-67-8)
- Semaglutide impurity 73 (CAS CATO-C4X-222673)
Why CATO?
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