N-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide CAS 844501-35-5
| CAS No. | 844501-35-5 |
| Molecular Formula | C14H19BFNO3 |
| Molecular Weight | 279.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 844501-35-5), molecular formula C14H19BFNO3 and molecular weight 279.11 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(3-Fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (C14H19BFNO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.5, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 279.11 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H19BFNO3 |
| Molecular Weight | 279.11 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related N Standards
- N-(4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1150271-55-8)
- N-(5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1150271-67-2)
- 7-Fluoro-3,4-dihydro-2H-1,4-benzoxazine-6-boronic acid pinacol ester, 97% (CAS 1256255-84-1)
- 8-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2h-benzo[b][1,4]oxazine (CAS 1256255-96-5)
- 5-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1256256-02-6)
- N-[2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetamide (CAS 1356943-52-6)
- 2-[3-Fluoro-4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]acetamide (CAS 1627857-32-2)
- N-(2-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetamide (CAS 1638329-59-5)
Recommended Standards
- Methyl 5-bromo-3-ureidothiophene-2-carboxylate (CAS 860354-59-2)
- 5-iodo-1H-indole-3-carbaldehyde (CAS 114144-17-1)
- Methyl 5-bromo-2-ureidothiophene-3-carboxylate (CAS 845889-21-6)
- 1-(4,6-Dichloro-1,3,5-triazin-2-yl)-2-methyl-2H-isoindole (CAS 118948-80-4)
- 1,4-phenylenediamine-<SUP>15</SUP>N<SUB>2</SUB> (CAS 119516-82-4)
- (1S,2R)-2-[(1,2-O-Isopropylidene)dihydroxyethyl]-6-fluorochroman-4-one (CAS 797054-21-8)
- 3-Bromo-4-morpholinoaniline (CAS 347324-26-9)
- N-(2-(3,5-Dimethyl-1H-pyrazol-1-yl)ethyl)-6-(1H-pyrazol-1-yl)pyridazine-3-carboxamide (CAS 1351595-22-6)
- N-(2-Methoxy-5-methylphenyl)-2-((3-(4-methoxyphenyl)-4-oxo-3,4,5,6,7,8-hexahydrobenzo[4,5]thieno[2,3-d]pyrimidin-2-yl)thio)acetamide (CAS 477330-54-4)
- α-Cyano-α-ethyl-1-cyclohexene-1-acetic Acid Ethyl Ester (CAS 7146-80-7)
- Ethyl 3-chloro-2,4-difluorobenzoate (CAS 1097886-66-2)
- 3-(2-Aminocyclohexyl)-1,3-thiazolidine-2,4-dione hydrochloride (CAS 1351643-24-7)
- (R)-2-(Aminomethyl)-1,4-dioxane Hydrochloride (CAS 1523541-84-5)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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